@kmcdonnell.bsky.social
We would also like to thank everyone at PTI for contributing to the project, it has been a huge team effort and a wonderful environment to work in!
6/7
6/7
May 28, 2025 at 11:40 AM
We would also like to thank everyone at PTI for contributing to the project, it has been a huge team effort and a wonderful environment to work in!
6/7
6/7
JMod can also provide highly accurate quantitation for these highly multiplexed samples, regardless of isotopic overlap
4/7
4/7
May 28, 2025 at 11:40 AM
JMod can also provide highly accurate quantitation for these highly multiplexed samples, regardless of isotopic overlap
4/7
4/7
In the context of plexDIA, JMod uniquely supports channel offsets of <4 Da. Using 2 Da offsets, it enables almost 2-fold more throughput for any given tag.
We demonstrate this using PSMtag, which was newly developed here at PTI, enabling 9-plexDIA!
3/7
www.biorxiv.org/content/10.1...
We demonstrate this using PSMtag, which was newly developed here at PTI, enabling 9-plexDIA!
3/7
www.biorxiv.org/content/10.1...
May 28, 2025 at 11:40 AM
In the context of plexDIA, JMod uniquely supports channel offsets of <4 Da. Using 2 Da offsets, it enables almost 2-fold more throughput for any given tag.
We demonstrate this using PSMtag, which was newly developed here at PTI, enabling 9-plexDIA!
3/7
www.biorxiv.org/content/10.1...
We demonstrate this using PSMtag, which was newly developed here at PTI, enabling 9-plexDIA!
3/7
www.biorxiv.org/content/10.1...
By modeling both MS1 and MS2 spectra as linear superpositions of library precursors, JMod can identify and quantify highly similar precursors within the same spectrum as well as deconvolve overlapping isotopes introduced by plexDIA.
2/7
2/7
May 28, 2025 at 11:40 AM
By modeling both MS1 and MS2 spectra as linear superpositions of library precursors, JMod can identify and quantify highly similar precursors within the same spectrum as well as deconvolve overlapping isotopes introduced by plexDIA.
2/7
2/7