Michael Kharas
kharaslab.bsky.social
Michael Kharas
@kharaslab.bsky.social
Professor scientist lab head
HAPPY 4th and excited to be part of this. Congrats to the talented Dr. Harold Elias for getting this epic Nature Comm story rdcu.be/euQb7 on how kitlow HSCs have superior thymic reconstitution. Big congrats to Marcel Van Den Brink and all of our collaborators!!

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Kitlo hematopoietic stem cells exhibit distinct lymphoid-primed chromatin landscapes that enhance thymic reconstitution
Nature Communications - Hematopoietic stem cells (HSCs) differentiate into multiple lineages, with such capacity impacted by aging. Here the authors identify Kitlo HSCs as a functionally distinct...
rdcu.be
July 4, 2025 at 3:47 PM
Reposted by Michael Kharas
So proud of this incredible work from @g-agarwal.bsky.social from our group with help from many fantastic folks in our lab and inspiring collaborators, including @kharaslab.bsky.social, Alex Bick, @yashpershad.bsky.social, and many others! Please check out Gaurav's awesome 🧵👇👇
What protects individuals from developing blood cancers?

Thrilled to share my work in @bloodgenes.bsky.social lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. 🧵👇 (1/n)
www.biorxiv.org/content/10.1...
March 27, 2025 at 8:36 PM