Kevin B Knopf
@kevinknopf.bsky.social
Hematologist/Oncologist, Health Services Researcher / Health Economist, whisky drinker
now Tom Lehrer - what a week this has been ;-(
July 27, 2025 at 8:42 PM
now Tom Lehrer - what a week this has been ;-(
Reposted by Kevin B Knopf
Only a subset of patients respond to immunotherapy
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
November 27, 2024 at 2:13 PM
Only a subset of patients respond to immunotherapy
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
Why? Which ones?
We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response.
www.nature.com/articles/s41...
Reposted by Kevin B Knopf
This is how we should be doing Oncology trials - the Dutch SONIA trial looking at treatment sequencing of CDK 4/6 inhibitors in advanced breast cancer. A self funding efficiency trial! #oncsky www.nature.com/articles/s41...
Early versus deferred use of CDK4/6 inhibitors in advanced breast cancer - Nature
The phase 3 SONIA trial challenges the benefits of using cyclin-dependent kinase 4 and 6 inhibitors as a first-line compared with second-line treatment.
www.nature.com
November 27, 2024 at 7:24 PM
This is how we should be doing Oncology trials - the Dutch SONIA trial looking at treatment sequencing of CDK 4/6 inhibitors in advanced breast cancer. A self funding efficiency trial! #oncsky www.nature.com/articles/s41...
Mill Valley after the rain
November 28, 2024 at 9:39 PM
Mill Valley after the rain
Went to hear Van Morrison in a small venue. He was fantastic.
Funny how his “North American tour is one town in New Hampshire and the rest in California.
Funny how his “North American tour is one town in New Hampshire and the rest in California.
November 19, 2024 at 8:21 PM
Went to hear Van Morrison in a small venue. He was fantastic.
Funny how his “North American tour is one town in New Hampshire and the rest in California.
Funny how his “North American tour is one town in New Hampshire and the rest in California.