Kesselslab
@kesselslab.bsky.social
Cellular and Computational Neuroscience group at the University of Amsterdam. PIs: Helmut Kessels, Erwin van Vliet, Pascal Chameau, Marlies Oostland, Bart Jongbloets, Sylvie Lesuis.
We are looking for an Assistant Professor in Healthy Longevity and Epilepsy to join the Cellular and Circuit Neuroscience team at the University of Amsterdam! werkenbij.uva.nl/en/vacancies... @sfn.org @fens.org @amsneuroscience.bsky.social @uva.nl @swammerdamuva.bsky.social
Vacancy — Assistant Professor in Healthy Longevity and Epilepsy
<p><span>Are you passionate about neuroscience and eager to contribute to groundbreaking research on healthy longevity and epilepsy? The Faculty of Science at the University of Amsterdam is looking for an ambitious Assistant Professor to join our interdisciplinary research team of the research group </span><a href="https://sils.uva.nl/content/research-groups/cellular-and-computational-neuroscience/cellular-and-circuit-neuroscience.html"><span>Cellular and Circuit Neuroscience</span></a><span>.</span></p>
werkenbij.uva.nl
November 20, 2025 at 8:44 AM
We are looking for an Assistant Professor in Healthy Longevity and Epilepsy to join the Cellular and Circuit Neuroscience team at the University of Amsterdam! werkenbij.uva.nl/en/vacancies... @sfn.org @fens.org @amsneuroscience.bsky.social @uva.nl @swammerdamuva.bsky.social
Wij zijn op zoek naar een neurobiologisch analist(e) om ons team in Amsterdam te versterken! Word jij onze enthousiaste nieuwe collega? Solliciteer dan nu! werkenbij.uva.nl/vacatures/ne... @uva.nl @swammerdamuva.bsky.social @amsneuroscience.bsky.social @fens.org @sfn.org
Vacature — Neurobiologisch Analist(e)
Ben je geïnteresseerd in hersenen en hersenziektes? Heb je altijd al onderzoek daarnaar willen helpen faciliteren? Vind je het leuk om in een interdisciplinaire onderzoek setting met veel jonge mensen daaraan mee te werken en hen te ondersteunen zodat hun proeven een succes worden? Dan maken wij graag kennis met jou!
werkenbij.uva.nl
November 12, 2025 at 3:24 PM
Wij zijn op zoek naar een neurobiologisch analist(e) om ons team in Amsterdam te versterken! Word jij onze enthousiaste nieuwe collega? Solliciteer dan nu! werkenbij.uva.nl/vacatures/ne... @uva.nl @swammerdamuva.bsky.social @amsneuroscience.bsky.social @fens.org @sfn.org
Reposted by Kesselslab
Indeed, we learned some valuable lessons throughout this project. This is a great summary by David of those lessons. One cannot underestimate the importance of incredibly careful data curation!
We certainly learned lots of lessons from this paper (e.g., need for standardizing pre-processing across labs and incredibly careful data curation, necessity of pharmacological blockade for opto-tagging in cerebellum, nearly complete inability to record granule cells using conventional probes).
February 28, 2025 at 6:28 PM
Indeed, we learned some valuable lessons throughout this project. This is a great summary by David of those lessons. One cannot underestimate the importance of incredibly careful data curation!
Reposted by Kesselslab
Our paper from the Cerebellum Cell-types Classification Collaboration (C4) is now out in Cell!
All data and software to run the classifier are available at www.c4-database.com.
Open-access link to the paper: authors.elsevier.com/c/1khABL7PXu...
All data and software to run the classifier are available at www.c4-database.com.
Open-access link to the paper: authors.elsevier.com/c/1khABL7PXu...
February 28, 2025 at 6:21 PM
Our paper from the Cerebellum Cell-types Classification Collaboration (C4) is now out in Cell!
All data and software to run the classifier are available at www.c4-database.com.
Open-access link to the paper: authors.elsevier.com/c/1khABL7PXu...
All data and software to run the classifier are available at www.c4-database.com.
Open-access link to the paper: authors.elsevier.com/c/1khABL7PXu...
Reposted by Kesselslab
🧠 What makes a memory stick? Not all neurons join a memory engram—only a select few. Our new study shows that the AMPA receptor subunit GluA1 keeps this process sparse and efficient. Without it, too many neurons activate, but memory gets worse!
🔗https://bit.ly/3CAx6TD
🔗https://bit.ly/3CAx6TD
February 11, 2025 at 7:38 AM
🧠 What makes a memory stick? Not all neurons join a memory engram—only a select few. Our new study shows that the AMPA receptor subunit GluA1 keeps this process sparse and efficient. Without it, too many neurons activate, but memory gets worse!
🔗https://bit.ly/3CAx6TD
🔗https://bit.ly/3CAx6TD
Reposted by Kesselslab
Sooo excited that my postdoc work with @sjo09.bsky.social is finally out! We explored the mechanisms behind stress-induced memory generalization, engram architecture, and the central role for endocannabinoids!
xcited to share our new results! We (huge team effort led by post-doc extraordinaire Sylvie Lesuis) examined the effects of acute stress on threat memory generalization and engram ensemble architecture.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Stress disrupts engram ensembles in lateral amygdala to generalize threat memory in mice
Stress induces aversive memory overgeneralization, a hallmark of many psychiatric disorders. Memories are encoded by a sparse ensemble of neurons acti…
www.sciencedirect.com
November 15, 2024 at 10:12 PM
Sooo excited that my postdoc work with @sjo09.bsky.social is finally out! We explored the mechanisms behind stress-induced memory generalization, engram architecture, and the central role for endocannabinoids!
New paper from our team on LRP1 expression in epilepsy and Alzheimer's Disease: sciencedirect.com/science/arti... Congratulations Annemieke and co-authors!
Cellular expression of low-density lipoprotein receptor-related protein 1 and amyloid beta deposition in human and rat epileptogenic brain
Decreased capillary expression of low-density lipoprotein receptor-related protein 1 (LRP1) has been linked to increased brain amyloid beta (Aβ) accum…
sciencedirect.com
January 27, 2025 at 2:55 PM
New paper from our team on LRP1 expression in epilepsy and Alzheimer's Disease: sciencedirect.com/science/arti... Congratulations Annemieke and co-authors!
Hello everyone! 👋 The Kesselslab (PIs: Helmut Kessels, Jan Gorter, Erwin van Vliet, Pascal Chameau, Natalie Cappaert, Marlies Oostland & Bart Jongbloets) from SILS at the University of Amsterdam has made the move from Twitter. We are looking forward to continuing the scientific conversation here.
January 27, 2025 at 2:37 PM
Hello everyone! 👋 The Kesselslab (PIs: Helmut Kessels, Jan Gorter, Erwin van Vliet, Pascal Chameau, Natalie Cappaert, Marlies Oostland & Bart Jongbloets) from SILS at the University of Amsterdam has made the move from Twitter. We are looking forward to continuing the scientific conversation here.