Kerstin Feistel
@kerstinfeistel.bsky.social
Developmental biologist trying to figure out why neural tubes close - or don‘t… Xenopus embryos participate in that effort.
Reposted by Kerstin Feistel
Great teamwork by the @wachtenlab.bsky.social @masslab.bsky.social and the May-Simera lab in our #FOR5547! Congratulations to the whole team!
🚨 New in The EMBO Journal!
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....
BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal
imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted
adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS
induces a a cell fa...
www.embopress.org
August 21, 2025 at 10:08 AM
Great teamwork by the @wachtenlab.bsky.social @masslab.bsky.social and the May-Simera lab in our #FOR5547! Congratulations to the whole team!
Reposted by Kerstin Feistel
Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia
May 14, 2025 at 9:09 PM
Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia
Reposted by Kerstin Feistel
Hallo #Fediverse, hallo liebe #Bluesky Community 👋! Die #UniHohenheim ist ab sofort auch am Start und informiert euch hier über Themen aus #Wissenschaft & Lehre, Hochschulpolitik, Erfolge der Uni und vieles mehr! Wir freuen uns 💚 auf den Austausch mit euch!
📸 Uni Hohenheim / Maximilian Pircher
📸 Uni Hohenheim / Maximilian Pircher
January 13, 2025 at 9:56 AM
Hallo #Fediverse, hallo liebe #Bluesky Community 👋! Die #UniHohenheim ist ab sofort auch am Start und informiert euch hier über Themen aus #Wissenschaft & Lehre, Hochschulpolitik, Erfolge der Uni und vieles mehr! Wir freuen uns 💚 auf den Austausch mit euch!
📸 Uni Hohenheim / Maximilian Pircher
📸 Uni Hohenheim / Maximilian Pircher
Reposted by Kerstin Feistel
Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade
Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...
www.biorxiv.org
January 11, 2025 at 7:51 PM
Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.