@kateonuska.bsky.social
Reposted
#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social
October 3, 2025 at 4:00 PM
#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social
Reposted
Latest paper is Vlad Novikov’s careful analysis of proteostasis in a TDP-43 mouse model
A Longitudinal Study of Sex Differences in a TDP‐43 Mouse Model Reveals STI1 Regulation of TDP‐43 Proteinopathy and Motor Deficits - Journal of Neurochemistry - onlinelibrary.wiley.com/doi/10.1111/...
A Longitudinal Study of Sex Differences in a TDP‐43 Mouse Model Reveals STI1 Regulation of TDP‐43 Proteinopathy and Motor Deficits - Journal of Neurochemistry - onlinelibrary.wiley.com/doi/10.1111/...
A Longitudinal Study of Sex Differences in a TDP‐43 Mouse Model Reveals STI1 Regulation of TDP‐43 Proteinopathy and Motor Deficits
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by abnormal accumulation of the RNA-binding protein TDP-43. Using a mouse model that mildly overexpresses human ...
onlinelibrary.wiley.com
August 23, 2025 at 11:25 AM
Latest paper is Vlad Novikov’s careful analysis of proteostasis in a TDP-43 mouse model
A Longitudinal Study of Sex Differences in a TDP‐43 Mouse Model Reveals STI1 Regulation of TDP‐43 Proteinopathy and Motor Deficits - Journal of Neurochemistry - onlinelibrary.wiley.com/doi/10.1111/...
A Longitudinal Study of Sex Differences in a TDP‐43 Mouse Model Reveals STI1 Regulation of TDP‐43 Proteinopathy and Motor Deficits - Journal of Neurochemistry - onlinelibrary.wiley.com/doi/10.1111/...
Reposted
Hot off the press Huge congrats to Alycia Crook a PhD student from the lab www.nature.com/articles/s41...
Characterization of a novel transgenic mouse model to investigate brain-wide activation of astrocyte Gq signaling - Lab Animal
This study uses a transgenic mouse line expressing Cre-inducible astro-hM3Dq to study astrocytes’ role in neuroinflammation and cognition without the use of viral transduction, mitigating the potentia...
www.nature.com
July 24, 2025 at 10:58 AM
Hot off the press Huge congrats to Alycia Crook a PhD student from the lab www.nature.com/articles/s41...
Reposted
Grad student extraordinaire @kateonuska.bsky.social dropped this preprint www.biorxiv.org/content/10.1... using
multimodal imaging, behavior, 🐁 and human datasets to show how cholinergic plasticity regulates resilience to Alzheimer’s pathology. Led by Taylor Schmitz 🧪
multimodal imaging, behavior, 🐁 and human datasets to show how cholinergic plasticity regulates resilience to Alzheimer’s pathology. Led by Taylor Schmitz 🧪
Cholinergic synaptic plasticity shapes resilience and vulnerability to tau
Synaptic dysfunction is a hallmark of Alzheimer’s disease (AD). Yet due to their plasticity, synapses may also adapt to early AD pathology. Using within-subject positron emission tomography scans targ...
www.biorxiv.org
June 13, 2025 at 10:31 PM
Grad student extraordinaire @kateonuska.bsky.social dropped this preprint www.biorxiv.org/content/10.1... using
multimodal imaging, behavior, 🐁 and human datasets to show how cholinergic plasticity regulates resilience to Alzheimer’s pathology. Led by Taylor Schmitz 🧪
multimodal imaging, behavior, 🐁 and human datasets to show how cholinergic plasticity regulates resilience to Alzheimer’s pathology. Led by Taylor Schmitz 🧪