Karolina Socha
karolinazsocha.bsky.social
Karolina Socha
@karolinazsocha.bsky.social
Assistant Project Scientists @UCLA investigating neural circuits underlying decision-making across species
Huge team effort 🚀 Congrats to all co-authors in @intlbrainlab.bsky.social for making this project and dataset possible!
September 5, 2025 at 6:24 PM
From 621,733 neurons recorded with 699 Neuropixels probes across 139 mice in 12 labs, we show that task signals—visual, choice, movement, prior—are distributed widely across the brain.
I hope these results inspire future projects. The data are public!
September 5, 2025 at 6:24 PM
Congrats Jean-Paul!!!
February 18, 2025 at 7:51 PM
It may take less than 5 years. That technology is just more complex and takes longer to produce than standard Npx probes.
February 12, 2025 at 7:57 PM
Project made possible by: @wellcometrust.bsky.social, @alleninstitute.bsky.social, @hhmijanelia.bsky.social, and other funders: IMEC, the NIH BRAIN Initiative, NTNU, Johns Hopkins University, UW, and @uclbrainscience.bsky.social.
February 12, 2025 at 9:34 AM
and to the Neuropixels Opto Consortium: @carandinilab.net, Barun Dutta, Tim Harris, Michael Häusser, @sonjahofer.bsky.social, @edvardmoser.bsky.social, Josh Siegle, @steinmetzneuro.bsky.social, and Karel Svoboda.
February 12, 2025 at 9:34 AM
to project collaborators: Alexander Ladd, Anna Bowen, Susu Chen, Jennifer Colonell, Anjal Doshi, Bill Karsh, Michael Krumin, Pavel Kulik, Anna Li, Meghan Olsen, Zhiwen Ye, Christof Koch, Jonathan T. Ting
February 12, 2025 at 9:34 AM
Huge kudos to the imec team: Pieter Neutens, Jan Putzeys, John O'Callaghan, Harrie A.C. Tilmans, and Marleen Welkenhuysen
February 12, 2025 at 9:34 AM
These probes let us evoke activity in neurons near the emitter sites, enabling spatial and temporal control across different depths of the mouse cortex.
February 12, 2025 at 9:34 AM
Some snippets of results: we successfully triggered activity in excitatory neurons expressing the red-shifted opsin ChRmine with both long and short light pulses. We show that the probes can be used for precise activation, identification, and manipulation of neuronal populations!
February 12, 2025 at 9:34 AM