Karin Cox
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karincox.bsky.social
Karin Cox
@karincox.bsky.social
Postdoctoral Scholar, Dept. of Neurobiology, University of Pittsburgh
Images: Pittsburghthreerivers, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons
https://legacyarttour.org/2010/01/blue-dog-2000-the-year-of-xerox.html
While these results await empirical validation, they raise interesting questions. To inhibit reflexes, what are the contributions of descending commands vs. local interactions? And do under-controlled reflexes contribute to slow/altered limb trajectories in movement disorders, including PD? (4/4)
December 25, 2025 at 8:25 AM
(2) Two modeled mechanisms (coordinated activation of α- and γ-motoneurons, or inhibition of γ-motoneurons by α-motoneuron collaterals) can effectively reduce such disruption. (3) However, neither mechanism is, in their words, a panacea -- meaningful disruption remained for some reaches. (3/4)
December 25, 2025 at 8:25 AM
Niyo et al. ask whether/how the nervous system prevents velocity-dependent stretch reflexes from disrupting voluntary movement. Observations from their model of a macaque arm: (1) Left disinhibited, stretch reflexes would substantially disrupt movements.
(2/4)
December 25, 2025 at 8:25 AM
Reposted by Karin Cox
The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23.

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6/n
Improving Performance, Accountability and Responsiveness in the Civil Service
The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...
www.federalregister.gov
April 23, 2025 at 6:17 PM