Karin Cox
@karincox.bsky.social
Postdoctoral Scholar, Dept. of Neurobiology, University of Pittsburgh
Images: Pittsburghthreerivers, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons
https://legacyarttour.org/2010/01/blue-dog-2000-the-year-of-xerox.html
Images: Pittsburghthreerivers, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons
https://legacyarttour.org/2010/01/blue-dog-2000-the-year-of-xerox.html
In 6-OHDA + MitoPark mice: Li et al. (www.nature.com/articles/s41...) report that (1) DBS inhibits STN neurons, reflecting greater drops in pre-synaptic glutamate vs. GABA release, and (2) chemogenetic inhibition of STN replicates the restorative effects of DBS on locomotion and rotarod tests.
January 10, 2026 at 5:26 PM
In 6-OHDA + MitoPark mice: Li et al. (www.nature.com/articles/s41...) report that (1) DBS inhibits STN neurons, reflecting greater drops in pre-synaptic glutamate vs. GABA release, and (2) chemogenetic inhibition of STN replicates the restorative effects of DBS on locomotion and rotarod tests.