Julien Klimmt
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julien-klimmt.bsky.social
Julien Klimmt
@julien-klimmt.bsky.social
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Postdoc @PaquetLab using novel stem-cell-derived 3D brain tissue models to study Alzheimer's disease
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Reposted by Julien Klimmt
paquetlab.bsky.social
Great talks and discussions at the 🧠 #SCMND meeting in Edinburgh this week, where @julien-klimmt.bsky.social from our lab presented our #ipsc 3D brain tissue model for #Alzheimer’s diseases to a full audience
March 29, 2025 at 6:59 AM
Reposted by Julien Klimmt
paquetlab.bsky.social
Open #Postdoc position @isd-research.bsky.social @lmumuenchen.bsky.social to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international Foundation Leducq Network of Excellence www.brenda-leducq.de Experience in vascular biology or related field required. Please RP and apply
The research group of Prof. Dr. Dominik Paquet (https://www.isd-research.de/paquetlab) is looking for a Postdoc. Our research involves the development of human brain tissue models to study the molecular mechanisms of Alzheimer's disease, Frontotemporal dementia, stroke and other related brain diseases and to develop therapeutic approaches. We use state-of-the-art molecular and cell biological methods, such as induced pluripotent stem cells (iPSCs), advanced molecular biology techniques, CRISPR/Cas9 genome editing, brain tissue engineering, scRNAseq, proteomics etc. We offer a highly international, versatile, extremely well equipped and productive work environment. We have received funding by an international research organization for a very interdisciplinary and collaborative project to develop a human iPSC model of the blood brain barrier and apply it to study neurovascular diseases, with a focus on Small vessel disease (SVD). The project will focus on CRISPR genome engineering of SVD-relevant mutations, differentiation of iPSCs into neurovascular cells, microfluidic 3D vascular tissue engineering, and identifying disease-relevant alterations by microscopy and omics techniques. It will be embedded in the highly collaborative and stimulating environment of the PaquetLab, ISD, SyNergy Cluster of Excellence, and our international collaboration network. We are looking for a highly motivated individual with the following skills: -extensive international scientific working experience in vascular biology or a closely related research field (required) -experience in molecular biology, biochemistry and/or omics techniques; cell culture experience is a plus -excellent English skills in speaking, writing about and presenting scientific data -interest in working in collaborative network of friendly scientists around the world A start date soon in 2025 is desired. Join us! dominik.paquet@med.uni-muenchen.de www.isd-research.de/paquetlab www.brenda-leducq.de
March 12, 2025 at 4:42 PM
julien-klimmt.bsky.social
Very happy to be selected as a speaker and present our 3D brain tissue model for AD research, I'm looking forward to seeing you in Edinburgh!
bowleslab.bsky.social Bowles Lab @bowleslab.bsky.social · Feb 19
Meet our 5 ECR speakers, selected from >160 abstract submissions!

You still have just over 2 weeks left to register for #SCMND2025!
Head to 👉 scmnd.com for more info!

@julien-klimmt.bsky.social @ukdri.ac.uk @cbdresearch.bsky.social @sheffielduni.bsky.social @ub.edu @lmumuenchen.bsky.social
February 19, 2025 at 5:30 PM