Julia M. Messmer
@juliammessmer.bsky.social
Scientist with a passion for cancer research
PostDoc @Institute of Experimental Oncology, Bonn, Germany
PostDoc @Institute of Experimental Oncology, Bonn, Germany
Reposted by Julia M. Messmer
I am excited to share our latest paper. We profiled CD8+ TILs from HPV- HNSCC patients using scRNA/TCRseq. In addition, we performed an ex vivo stimulation of cells to capture their transcriptional response. 1/n
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Type I Interferon Drives a Cellular State Inert to TCR‐Stimulation and Could Impede Effective T‐Cell Differentiation in Cancer
Multimodal single-cell RNA sequencing identified a population of CD8+ T cells elevated in tumor tissue enriched for interferon-stimulated genes (ISG). These ISG cells are clonally related to a popula...
onlinelibrary.wiley.com
November 17, 2024 at 12:47 PM
I am excited to share our latest paper. We profiled CD8+ TILs from HPV- HNSCC patients using scRNA/TCRseq. In addition, we performed an ex vivo stimulation of cells to capture their transcriptional response. 1/n
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Julia M. Messmer
How do T cells reach melanoma brain tumors?
Using in vivo microscopy 🔬🐭, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels.
We recently published this work in Immunity: authors.elsevier.com/sd/article/S...
Using in vivo microscopy 🔬🐭, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels.
We recently published this work in Immunity: authors.elsevier.com/sd/article/S...
November 20, 2024 at 3:00 PM
How do T cells reach melanoma brain tumors?
Using in vivo microscopy 🔬🐭, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels.
We recently published this work in Immunity: authors.elsevier.com/sd/article/S...
Using in vivo microscopy 🔬🐭, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels.
We recently published this work in Immunity: authors.elsevier.com/sd/article/S...