juhyunk.bsky.social
@juhyunk.bsky.social
Reposted by juhyunk.bsky.social
Our featured article: DNA methylation in mammalian development and disease go.nature.com/3X14Ali #Review by Zachary D. Smith @yaleschoolofmed.bsky.social, Sara Hetzel & Alexander Meissner @molgen.mpg.de
Free to read here: rdcu.be/dQEND
Free to read here: rdcu.be/dQEND
DNA methylation in mammalian development and disease - Nature Reviews Genetics
In this Review, Smith et al. describe DNA methylation landscapes that emerge over mammalian development and within key disease states, as well as how different methyltransferases interface w...
go.nature.com
December 13, 2024 at 12:57 PM
Our featured article: DNA methylation in mammalian development and disease go.nature.com/3X14Ali #Review by Zachary D. Smith @yaleschoolofmed.bsky.social, Sara Hetzel & Alexander Meissner @molgen.mpg.de
Free to read here: rdcu.be/dQEND
Free to read here: rdcu.be/dQEND
Reposted by juhyunk.bsky.social
This project stands together with work from @sudpinglay.bsky.social and @jshendure.bsky.social , who came up with an alternative method that includes a clever, single-cell sequencing strategy to read out the variants generated by scrambling.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Multiplex generation and single-cell analysis of structural variants in mammalian genomes
Studying the functional consequences of structural variants (SVs) in mammalian genomes is challenging because (i) SVs arise much less commonly than single-nucleotide variants or small indels and (ii) ...
www.science.org
January 31, 2025 at 1:49 PM
This project stands together with work from @sudpinglay.bsky.social and @jshendure.bsky.social , who came up with an alternative method that includes a clever, single-cell sequencing strategy to read out the variants generated by scrambling.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...