Justine Couble
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ju-couble.bsky.social
Justine Couble
@ju-couble.bsky.social
Just finished my PhD in molecular parasitology at @pasteur.fr 🧬 | Forever curious about parasites 🦠🪱 | Scuba diver & passionate backpacker 🤿🌍| Exploring science and the world, one adventure at a time!
Reposted by Justine Couble
How does the malaria parasite regulate co-expression of genes? By recruiting them into transcription factories, courtesy of MORC et al. A fantastic team effort led by @jessmbryant.bsky.social with Jacques Serizay @singh-parul.bsky.social, @ju-couble.bsky.social @rkoszul.bsky.social
June 30, 2025 at 11:36 AM
Thrilled to share that the main part of my PhD work is now on bioRxiv!
Curious about how Plasmodium regulates its ribosomes? Check it out!
Led by @sebbaumgarten.bsky.social with great collaboration from @tizvignolini.bsky.social

www.biorxiv.org/content/10.1...
A metabolism-chromatin axis promotes ribosome heterogeneity in the human malaria parasite
The transmission of the most virulent human malaria parasite, Plasmodium falciparum, relies on its survival in the contrasting environments of the human host and mosquito vector. One of the most fasci...
www.biorxiv.org
April 17, 2025 at 9:01 AM
Reposted by Justine Couble
Ready for the most beautifully sophisticated m6A modification program out there?

It’s sex-specific, controls a developmental transition and is temperature-sensitive. Dream team led by Selina, with @ameyasinha.bsky.social @jessmbryant.bsky.social @tizvignolini.bsky.social @ju-couble.bsky.social
N6-methyladenosine primes the malaria parasite for transmission
Sudden environmental changes are a recurring challenge for unicellular organisms, but a necessity for many to progress through their lifecycle. To transmit from its human host to mosquito vector, mala...
doi.org
April 4, 2025 at 9:32 AM
Reposted by Justine Couble
Malaria parasites are an extreme example of ribosome heterogeneity. But how do they control which ribosomal RNA to express when?

Check out this mountain of work led by @ju-couble.bsky.social with @tizvignolini.bsky.social @jessmbryant.bsky.social

www.biorxiv.org/content/10.1...
www.biorxiv.org
March 26, 2025 at 7:45 AM