Jonathan Richard
@jrichard-phd.bsky.social
Virologue (Ph. D.), mari, papa, fan du CH, CFMTL et Arsenal. Curieux de science, sport et politique /Virologist (Ph.D.), husband, dad, fan of the Habs, CFMTL, and Arsenal. Curious about science, sports, and politics.
We have recently launched a clinical trial to evaluate whether Fostemsavir can reduce inflammation and prevent cardiovascular disease in PLWH with detectable levels of gp120 in their blood.
October 17, 2025 at 11:10 AM
We have recently launched a clinical trial to evaluate whether Fostemsavir can reduce inflammation and prevent cardiovascular disease in PLWH with detectable levels of gp120 in their blood.
We previously demonstrated that it also blocks the immunomodulatory activities of soluble gp120
www.cell.com/cell-chemica...
www.cell.com/cell-chemica...
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120
Richard et al. provide extensive evidence suggesting that treatment with the HIV-1
attachment inhibitor temsavir can have beneficial effects that extend beyond viral
neutralization, notably by prevent...
www.cell.com
October 17, 2025 at 11:09 AM
We previously demonstrated that it also blocks the immunomodulatory activities of soluble gp120
www.cell.com/cell-chemica...
www.cell.com/cell-chemica...
Yes, and this could be tested using Fostemsavir (see the following paper).
academic.oup.com/jid/advance-...
academic.oup.com/jid/advance-...
Fostemsavir Decreases the Levels of Anti-gp120 CD4-Induced Antibodies in Heavily Treatment-Experienced People With HIV
Anti-gp120 CD4-induced antibodies are associated with CD4 depletion in vitro and in heavily treatment-experienced people with HIV. Fostemsavir treatment re
academic.oup.com
October 17, 2025 at 11:04 AM
Yes, and this could be tested using Fostemsavir (see the following paper).
academic.oup.com/jid/advance-...
academic.oup.com/jid/advance-...