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Enhanced FIB-SEM Technology
@jrc-efib-tech.bsky.social
New preprint! eFIB-SEM unlocks stunning 3D views of biology, but streaks—the “curtain effect”—impact the micrographs. We demonstrate a simple tweak that significantly reduces these artefacts. Thrilled to share this work with the Hess lab @ HHMI/Janelia!
📝 www.biorxiv.org/content/10.1...
September 26, 2025 at 11:13 PM
Reposted by Enhanced FIB-SEM Technology
📢 Submissions are now open for the CellMap Segmentation Challenge.

Build the best method for segmenting cellular organelles in vEM using our 289 annotated volumes, 40 organelle classes, and 22 diverse cell and tissue types.

🔗 hhmi.news/410evJQ
February 5, 2025 at 4:09 PM
Reposted by Enhanced FIB-SEM Technology
On this day 5 years ago #HHMIJanelia and Google released the "hemibrain", a map of neural connections in much of the #Drosophila fly brain. At the time it was the largest such #connectome ever created. Here's a video from the release (polished a bit), showing the interesting shapes of the neurons.
January 22, 2025 at 9:35 AM
Reposted by Enhanced FIB-SEM Technology
9️⃣ Janelia’s Advanced Imaging Center @aicjanelia.bsky.social marked 10 years of pushing microscopy forward. Since 2014, the AIC has given hundreds of researchers access to cutting-edge microscopes, at no cost. 🔬
https://buff.ly/3ZUmmXT
December 30, 2024 at 3:01 PM
Reposted by Enhanced FIB-SEM Technology
🦠A team led by the Lippincott-Schwartz Lab used a new technique developed at Janelia called high-resolution template matching, or HRTM, to uncover in unprecedented detail the movement of ribosomes – the molecular structures that synthesize proteins inside cells.

🔗 hhmi.news/401LKMq
December 19, 2024 at 3:26 PM