Jotbody-Beyond Affinity-
@jotbody.bsky.social
Empowering Science with Precision
Biotechnology Research• Hong Kong
Biotechnology Research• Hong Kong
💪 Small in size, strong in performance
Anti-PD-L1 VHH Antibody (JOT0002-5) by Jotbody: precise PD-L1 detection (ELISA/WB/IHC/IF/FC), 14.4 kDa, KD=0.363 nM. Ideal for research & diagnostics.
#PDL1 #VHH #nanobody #lifescience #biotech #researchtools
Anti-PD-L1 VHH Antibody (JOT0002-5) by Jotbody: precise PD-L1 detection (ELISA/WB/IHC/IF/FC), 14.4 kDa, KD=0.363 nM. Ideal for research & diagnostics.
#PDL1 #VHH #nanobody #lifescience #biotech #researchtools
November 6, 2025 at 7:48 AM
💪 Small in size, strong in performance
Anti-PD-L1 VHH Antibody (JOT0002-5) by Jotbody: precise PD-L1 detection (ELISA/WB/IHC/IF/FC), 14.4 kDa, KD=0.363 nM. Ideal for research & diagnostics.
#PDL1 #VHH #nanobody #lifescience #biotech #researchtools
Anti-PD-L1 VHH Antibody (JOT0002-5) by Jotbody: precise PD-L1 detection (ELISA/WB/IHC/IF/FC), 14.4 kDa, KD=0.363 nM. Ideal for research & diagnostics.
#PDL1 #VHH #nanobody #lifescience #biotech #researchtools
When nanobodies are immobilized directionally via SpyTag/SpyCatcher (90% coupling efficiency), binding capacity triples—and achieves >95% purity from serum with outstanding reuse.
jotbody.com/could-proper...
jotbody.com/could-proper...
August 21, 2025 at 3:00 AM
When nanobodies are immobilized directionally via SpyTag/SpyCatcher (90% coupling efficiency), binding capacity triples—and achieves >95% purity from serum with outstanding reuse.
jotbody.com/could-proper...
jotbody.com/could-proper...
Plasma EV tau isoform ratios (3R/4R) and TDP-43 levels can distinguish FTD, ALS & PSP with over 90% accuracy—a promising step toward a non-invasive liquid biopsy. #EVs #Neurodegeneration
🔗 Read more about their research: jotbody.com/what-if-extr...
🔗 Read more about their research: jotbody.com/what-if-extr...
August 19, 2025 at 2:42 AM
Plasma EV tau isoform ratios (3R/4R) and TDP-43 levels can distinguish FTD, ALS & PSP with over 90% accuracy—a promising step toward a non-invasive liquid biopsy. #EVs #Neurodegeneration
🔗 Read more about their research: jotbody.com/what-if-extr...
🔗 Read more about their research: jotbody.com/what-if-extr...
🔍 Can nanobodies transform industrial protein purification?
NbHB1 resin hit 96% purity, 81% recovery, stayed stable for 25 cycles, & leaked <1.7 ng/mL ligand.
A leap forward for scalable rHBsAg-VLP production.
Read more: jotbody.com/can-nanobodi...
NbHB1 resin hit 96% purity, 81% recovery, stayed stable for 25 cycles, & leaked <1.7 ng/mL ligand.
A leap forward for scalable rHBsAg-VLP production.
Read more: jotbody.com/can-nanobodi...
August 12, 2025 at 9:30 AM
🔍 Can nanobodies transform industrial protein purification?
NbHB1 resin hit 96% purity, 81% recovery, stayed stable for 25 cycles, & leaked <1.7 ng/mL ligand.
A leap forward for scalable rHBsAg-VLP production.
Read more: jotbody.com/can-nanobodi...
NbHB1 resin hit 96% purity, 81% recovery, stayed stable for 25 cycles, & leaked <1.7 ng/mL ligand.
A leap forward for scalable rHBsAg-VLP production.
Read more: jotbody.com/can-nanobodi...
❓ What if CRISPR could be delivered safely to brain cells without virus? A new EV platform shows >40% hippocampal editing in vivo—game changer.
📖 Read more: jotbody.com/are-evs-the-...
📖 Read more: jotbody.com/are-evs-the-...
August 5, 2025 at 2:30 AM
❓ What if CRISPR could be delivered safely to brain cells without virus? A new EV platform shows >40% hippocampal editing in vivo—game changer.
📖 Read more: jotbody.com/are-evs-the-...
📖 Read more: jotbody.com/are-evs-the-...
VS2 nanobody resin binds 16.23 mg/mL of SUMO fusion protein, works across eight targets, and retains >80% capacity after 25 NaOH cleans. Efficient purification, redefined.
🔗 jotbody.com/can-nanobody...
🔗 jotbody.com/can-nanobody...
July 30, 2025 at 2:19 AM
VS2 nanobody resin binds 16.23 mg/mL of SUMO fusion protein, works across eight targets, and retains >80% capacity after 25 NaOH cleans. Efficient purification, redefined.
🔗 jotbody.com/can-nanobody...
🔗 jotbody.com/can-nanobody...
Can dopamine coated EVs target dopamine neurons and stop Parkinson’s damage?
🔬 Dopa EVs show targeted uptake, rescue dopaminergic neurons, and trigger protective autophagy in mouse PD models.
jotbody.com/can-dopamine...
🔬 Dopa EVs show targeted uptake, rescue dopaminergic neurons, and trigger protective autophagy in mouse PD models.
jotbody.com/can-dopamine...
July 29, 2025 at 2:58 AM
Can dopamine coated EVs target dopamine neurons and stop Parkinson’s damage?
🔬 Dopa EVs show targeted uptake, rescue dopaminergic neurons, and trigger protective autophagy in mouse PD models.
jotbody.com/can-dopamine...
🔬 Dopa EVs show targeted uptake, rescue dopaminergic neurons, and trigger protective autophagy in mouse PD models.
jotbody.com/can-dopamine...
Could EVs carry RNA therapies—safely & efficiently without viruses?
✅ EVs deliver miRNA, mRNA, and CRISPR guides across the BBB & tumors with low immune risk.
Read more about the review: jotbody.com/could-extrac...
✅ EVs deliver miRNA, mRNA, and CRISPR guides across the BBB & tumors with low immune risk.
Read more about the review: jotbody.com/could-extrac...
July 23, 2025 at 2:34 AM
Could EVs carry RNA therapies—safely & efficiently without viruses?
✅ EVs deliver miRNA, mRNA, and CRISPR guides across the BBB & tumors with low immune risk.
Read more about the review: jotbody.com/could-extrac...
✅ EVs deliver miRNA, mRNA, and CRISPR guides across the BBB & tumors with low immune risk.
Read more about the review: jotbody.com/could-extrac...
🧬Nanobody-based AuNP cluster LFIA rapidly detects survivin in urine—LOD just 3.90 ng/mL. Fast, stable & precise bladder cancer diagnosis in minutes, no labs needed!
🔗https://jotbody.com/can-nanobody-strips-outsmart-invasive-bladder-cancer-tests/
#Nanobody #IVD #BladderCancer #Diagnostics #RapidTest
🔗https://jotbody.com/can-nanobody-strips-outsmart-invasive-bladder-cancer-tests/
#Nanobody #IVD #BladderCancer #Diagnostics #RapidTest
July 16, 2025 at 6:12 AM
🧬Nanobody-based AuNP cluster LFIA rapidly detects survivin in urine—LOD just 3.90 ng/mL. Fast, stable & precise bladder cancer diagnosis in minutes, no labs needed!
🔗https://jotbody.com/can-nanobody-strips-outsmart-invasive-bladder-cancer-tests/
#Nanobody #IVD #BladderCancer #Diagnostics #RapidTest
🔗https://jotbody.com/can-nanobody-strips-outsmart-invasive-bladder-cancer-tests/
#Nanobody #IVD #BladderCancer #Diagnostics #RapidTest
🔬 Nanobody rapid test detects NMP22 & survivin for bladder cancer:
• 100% sensitivity, 90.9% specificity (dual marker strip)
• Visual results in minutes
📖 Read:https://jotbody.com/can-a-nanobody-urine-strip-outperform-invasive-bladder-cancer-screening/
• 100% sensitivity, 90.9% specificity (dual marker strip)
• Visual results in minutes
📖 Read:https://jotbody.com/can-a-nanobody-urine-strip-outperform-invasive-bladder-cancer-screening/
July 9, 2025 at 3:47 AM
🔬 Nanobody rapid test detects NMP22 & survivin for bladder cancer:
• 100% sensitivity, 90.9% specificity (dual marker strip)
• Visual results in minutes
📖 Read:https://jotbody.com/can-a-nanobody-urine-strip-outperform-invasive-bladder-cancer-screening/
• 100% sensitivity, 90.9% specificity (dual marker strip)
• Visual results in minutes
📖 Read:https://jotbody.com/can-a-nanobody-urine-strip-outperform-invasive-bladder-cancer-screening/
✨ Nanobody Breakthrough in Zika Detection! 🦠
Nanobody test detects 1 ng/mL Zika NS1, results in 15 minutes ⏱️, no Dengue cross-reaction. Affordable, portable, and stable for 28 days 🌡️—ideal for self-testing.
🔗 jotbody.com/could-a-smal...
#Nanobody #IVD #Diagnostics #Zika
Nanobody test detects 1 ng/mL Zika NS1, results in 15 minutes ⏱️, no Dengue cross-reaction. Affordable, portable, and stable for 28 days 🌡️—ideal for self-testing.
🔗 jotbody.com/could-a-smal...
#Nanobody #IVD #Diagnostics #Zika
July 3, 2025 at 6:18 AM
✨ Nanobody Breakthrough in Zika Detection! 🦠
Nanobody test detects 1 ng/mL Zika NS1, results in 15 minutes ⏱️, no Dengue cross-reaction. Affordable, portable, and stable for 28 days 🌡️—ideal for self-testing.
🔗 jotbody.com/could-a-smal...
#Nanobody #IVD #Diagnostics #Zika
Nanobody test detects 1 ng/mL Zika NS1, results in 15 minutes ⏱️, no Dengue cross-reaction. Affordable, portable, and stable for 28 days 🌡️—ideal for self-testing.
🔗 jotbody.com/could-a-smal...
#Nanobody #IVD #Diagnostics #Zika
🧬 Hybrid EVs hit ≈40% loading efficiency for siRNA/plasmids using a 30-min pH-triggered fusion with LCNPs—double the performance of passive methods.
Surface proteins and function intact.
🔗 jotbody.com/why-loading-...
#EVResearch #GeneDelivery
Surface proteins and function intact.
🔗 jotbody.com/why-loading-...
#EVResearch #GeneDelivery
July 2, 2025 at 6:14 AM
🧬 Hybrid EVs hit ≈40% loading efficiency for siRNA/plasmids using a 30-min pH-triggered fusion with LCNPs—double the performance of passive methods.
Surface proteins and function intact.
🔗 jotbody.com/why-loading-...
#EVResearch #GeneDelivery
Surface proteins and function intact.
🔗 jotbody.com/why-loading-...
#EVResearch #GeneDelivery
🎯 Nanobody raises extracellular pH by ~0.11 units
🚫 Blocks invasion (Ki ≈ 15.6 nM)
🌬 Lung metastasis drops 50% → 13% in mice (~74% reduction)
✅ No tumor shrinkage or toxicity
Oncotarget study 👇
jotbody.com/could-one-ti...
🚫 Blocks invasion (Ki ≈ 15.6 nM)
🌬 Lung metastasis drops 50% → 13% in mice (~74% reduction)
✅ No tumor shrinkage or toxicity
Oncotarget study 👇
jotbody.com/could-one-ti...
June 24, 2025 at 7:25 AM
🎯 Nanobody raises extracellular pH by ~0.11 units
🚫 Blocks invasion (Ki ≈ 15.6 nM)
🌬 Lung metastasis drops 50% → 13% in mice (~74% reduction)
✅ No tumor shrinkage or toxicity
Oncotarget study 👇
jotbody.com/could-one-ti...
🚫 Blocks invasion (Ki ≈ 15.6 nM)
🌬 Lung metastasis drops 50% → 13% in mice (~74% reduction)
✅ No tumor shrinkage or toxicity
Oncotarget study 👇
jotbody.com/could-one-ti...
Nanobodies are revolutionizing cancer therapy by targeting the tumor microenvironment for precise drug delivery, including:
Glioblastoma Invasion Inhibition
Enhanced Imaging in Gastric Cancer
Targeted Photodynamic Therapy
Discover the latest research: jotbody.com/nanobodies-p...
Glioblastoma Invasion Inhibition
Enhanced Imaging in Gastric Cancer
Targeted Photodynamic Therapy
Discover the latest research: jotbody.com/nanobodies-p...
June 3, 2025 at 9:21 AM
Nanobodies are revolutionizing cancer therapy by targeting the tumor microenvironment for precise drug delivery, including:
Glioblastoma Invasion Inhibition
Enhanced Imaging in Gastric Cancer
Targeted Photodynamic Therapy
Discover the latest research: jotbody.com/nanobodies-p...
Glioblastoma Invasion Inhibition
Enhanced Imaging in Gastric Cancer
Targeted Photodynamic Therapy
Discover the latest research: jotbody.com/nanobodies-p...
Milk-derived extracellular vesicles (mEVs) offer natural therapeutic benefits and can be engineered for targeted drug delivery, including oral administration.
Learn more: link.springer.com/article/10.1...
Learn more: link.springer.com/article/10.1...
May 27, 2025 at 2:03 AM
Milk-derived extracellular vesicles (mEVs) offer natural therapeutic benefits and can be engineered for targeted drug delivery, including oral administration.
Learn more: link.springer.com/article/10.1...
Learn more: link.springer.com/article/10.1...
Can humanized nanobodies match native performance?
Yes! A 2024 study shows CD19 CAR-Ts with humanized VHHs retained full cytotoxicity.
🔗 jotbody.com/can-humanize...
Yes! A 2024 study shows CD19 CAR-Ts with humanized VHHs retained full cytotoxicity.
🔗 jotbody.com/can-humanize...
May 13, 2025 at 10:01 AM
Can humanized nanobodies match native performance?
Yes! A 2024 study shows CD19 CAR-Ts with humanized VHHs retained full cytotoxicity.
🔗 jotbody.com/can-humanize...
Yes! A 2024 study shows CD19 CAR-Ts with humanized VHHs retained full cytotoxicity.
🔗 jotbody.com/can-humanize...
Plant nanoparticles from red cabbage cut gut inflammation by 50%! Engineered vesicles safely targeted and repaired colon damage orally. Future IBD treatment? 🌿
jotbody.com/plant-derive...
jotbody.com/plant-derive...
May 13, 2025 at 6:45 AM
Plant nanoparticles from red cabbage cut gut inflammation by 50%! Engineered vesicles safely targeted and repaired colon damage orally. Future IBD treatment? 🌿
jotbody.com/plant-derive...
jotbody.com/plant-derive...
Researchers engineered two nanobodies that bind to Ebola to neutralise viral particles in vitro.
🚀 The result:
• Animal Survival: 50% longer survival day.
• Viral Load Reduction: Up to 1,000-fold decrease.
Read more about the study: jotbody.com/event_catego...
🚀 The result:
• Animal Survival: 50% longer survival day.
• Viral Load Reduction: Up to 1,000-fold decrease.
Read more about the study: jotbody.com/event_catego...
May 6, 2025 at 4:13 PM
Researchers engineered two nanobodies that bind to Ebola to neutralise viral particles in vitro.
🚀 The result:
• Animal Survival: 50% longer survival day.
• Viral Load Reduction: Up to 1,000-fold decrease.
Read more about the study: jotbody.com/event_catego...
🚀 The result:
• Animal Survival: 50% longer survival day.
• Viral Load Reduction: Up to 1,000-fold decrease.
Read more about the study: jotbody.com/event_catego...
🌳 Plant-derived extracellular vesicles (PDEVs) are emerging as sustainable, biocompatible nanocarriers for drug delivery.
📖 Dive into the latest research: jotbody.com/plant-derive...
📖 Dive into the latest research: jotbody.com/plant-derive...
May 6, 2025 at 4:32 AM
🌳 Plant-derived extracellular vesicles (PDEVs) are emerging as sustainable, biocompatible nanocarriers for drug delivery.
📖 Dive into the latest research: jotbody.com/plant-derive...
📖 Dive into the latest research: jotbody.com/plant-derive...
With a projected CAGR of 18.5%, the global extracellular vesicle market. With a projected compound annual growth rate (CAGR) of 18.5%, the global EV Diagnostics & Therapeutics market EV market is expected to reach $3.28 billion by 2030.
Read more: jotbody.com/the-booming-...
Read more: jotbody.com/the-booming-...
April 22, 2025 at 5:55 AM
With a projected CAGR of 18.5%, the global extracellular vesicle market. With a projected compound annual growth rate (CAGR) of 18.5%, the global EV Diagnostics & Therapeutics market EV market is expected to reach $3.28 billion by 2030.
Read more: jotbody.com/the-booming-...
Read more: jotbody.com/the-booming-...
🥜 Are your current food allergen detection methods sensitive and reliable enough? A recent review in Food Quality and Safety demonstrates that nanobody-based immunoassays are setting new standards for food allergen surveillance. Read more : jotbody.com/nanobodies-r...
April 22, 2025 at 5:53 AM
🥜 Are your current food allergen detection methods sensitive and reliable enough? A recent review in Food Quality and Safety demonstrates that nanobody-based immunoassays are setting new standards for food allergen surveillance. Read more : jotbody.com/nanobodies-r...
🦈 Shark - derived nanobodies target CD22 in cancer immunotherapy. Conventional CD22 - positive B - cell malignancy therapies have issues. CD22 is a great immunotherapy target. A study in Molecular Therapy – Oncolytics by Scott McComb, Read more: jotbody.com/revolutioniz...
April 9, 2025 at 2:11 AM
🦈 Shark - derived nanobodies target CD22 in cancer immunotherapy. Conventional CD22 - positive B - cell malignancy therapies have issues. CD22 is a great immunotherapy target. A study in Molecular Therapy – Oncolytics by Scott McComb, Read more: jotbody.com/revolutioniz...
🌿 Plant-Based EVs: A New Era for Targeted Skincare Innovation UV radiation harms skin. A study in the Asian Journal of Pharmaceutical Sciences has a new founding that EVs and liposome systems can fight UV - induced skin inflammation. Read more: jotbody.com/hybrid-nanov...
March 25, 2025 at 8:52 AM
🌿 Plant-Based EVs: A New Era for Targeted Skincare Innovation UV radiation harms skin. A study in the Asian Journal of Pharmaceutical Sciences has a new founding that EVs and liposome systems can fight UV - induced skin inflammation. Read more: jotbody.com/hybrid-nanov...
🚀 Can AI Revolutionize #Nanobody Discovery?
New Journal of Nanobiotech study: AI speeds nanobody design & interaction optimization.
🔍 Key: AI cuts screening, ML boosts stability, makes treatments faster/cheaper.
Benefits precision med, cancer & infectious disease.
📖 Read: lnkd.in/g3FRRyh6
New Journal of Nanobiotech study: AI speeds nanobody design & interaction optimization.
🔍 Key: AI cuts screening, ML boosts stability, makes treatments faster/cheaper.
Benefits precision med, cancer & infectious disease.
📖 Read: lnkd.in/g3FRRyh6
March 12, 2025 at 3:34 AM
🚀 Can AI Revolutionize #Nanobody Discovery?
New Journal of Nanobiotech study: AI speeds nanobody design & interaction optimization.
🔍 Key: AI cuts screening, ML boosts stability, makes treatments faster/cheaper.
Benefits precision med, cancer & infectious disease.
📖 Read: lnkd.in/g3FRRyh6
New Journal of Nanobiotech study: AI speeds nanobody design & interaction optimization.
🔍 Key: AI cuts screening, ML boosts stability, makes treatments faster/cheaper.
Benefits precision med, cancer & infectious disease.
📖 Read: lnkd.in/g3FRRyh6
Can tomatoes deliver cancer drugs? Indian researchers show tomato-derived EVs enhance drug delivery & targeting in colon cancer. A scalable, natural approach for future therapies.
🔗 jotbody.com/can-tomatoes...
🔗 jotbody.com/can-tomatoes...
March 5, 2025 at 1:54 AM
Can tomatoes deliver cancer drugs? Indian researchers show tomato-derived EVs enhance drug delivery & targeting in colon cancer. A scalable, natural approach for future therapies.
🔗 jotbody.com/can-tomatoes...
🔗 jotbody.com/can-tomatoes...