Julie Ostrander
@jostrander.bsky.social
Associate Professor of Medicine at the University of Minnesota.
This has been such an exciting collaborative project with the lab of @mjsikora.bsky.social! Stay tuned… more to come!
We did a thing w @jostrander.bsky.social!
Over the last few years, we took a new direction into #lobular breast cancer oncogenesis. We know loss of the gene CDH1 (E-cadherin) is central to ILC, and is among its earliest oncogenic events. But why? How does this push normal breast toward cancer? 1/n
Over the last few years, we took a new direction into #lobular breast cancer oncogenesis. We know loss of the gene CDH1 (E-cadherin) is central to ILC, and is among its earliest oncogenic events. But why? How does this push normal breast toward cancer? 1/n
CDH1 loss remodels gene expression and lineage identity in human mammary epithelial cells https://www.biorxiv.org/content/10.1101/2025.06.20.660633v1
June 25, 2025 at 10:50 PM
This has been such an exciting collaborative project with the lab of @mjsikora.bsky.social! Stay tuned… more to come!
Reposted by Julie Ostrander
Congrats to Dr. Maggie Musick on her 1st lead-author study in the lab! This #lobular project with @jostrander.bsky.social has been so much fun over the last few years.
Blue-torial soon, after a grant gets out the door this week 🫠
Blue-torial soon, after a grant gets out the door this week 🫠
CDH1 loss remodels gene expression and lineage identity in human mammary epithelial cells https://www.biorxiv.org/content/10.1101/2025.06.20.660633v1
June 23, 2025 at 2:35 PM
Congrats to Dr. Maggie Musick on her 1st lead-author study in the lab! This #lobular project with @jostrander.bsky.social has been so much fun over the last few years.
Blue-torial soon, after a grant gets out the door this week 🫠
Blue-torial soon, after a grant gets out the door this week 🫠
Reposted by Julie Ostrander
CDH1 loss remodels gene expression and lineage identity in human mammary epithelial cells https://www.biorxiv.org/content/10.1101/2025.06.20.660633v1
June 23, 2025 at 12:50 AM
Reposted by Julie Ostrander
ASSIGNMENT: COMMENT ON SCHEDULE F
1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.
www.regulations.gov/commenton/OP...
1/n
1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.
www.regulations.gov/commenton/OP...
1/n
Regulations.gov
www.regulations.gov
May 31, 2025 at 1:48 PM
ASSIGNMENT: COMMENT ON SCHEDULE F
1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.
www.regulations.gov/commenton/OP...
1/n
1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees.
www.regulations.gov/commenton/OP...
1/n
Reposted by Julie Ostrander
NIH has terminated at least 565 previously awarded training grants, fellowships, and early career awards so far this year, and they've awarded 1,100 fewer new ones.
That's ~1,600 fewer grants supporting new scientists than we'd have had if just a few thousand more folks voted for Harris over Trump.
That's ~1,600 fewer grants supporting new scientists than we'd have had if just a few thousand more folks voted for Harris over Trump.
May 27, 2025 at 4:08 PM
NIH has terminated at least 565 previously awarded training grants, fellowships, and early career awards so far this year, and they've awarded 1,100 fewer new ones.
That's ~1,600 fewer grants supporting new scientists than we'd have had if just a few thousand more folks voted for Harris over Trump.
That's ~1,600 fewer grants supporting new scientists than we'd have had if just a few thousand more folks voted for Harris over Trump.
Reposted by Julie Ostrander
My daughter’s speech therapist went out of business because Medicaid reimbursement rates were too low. We do not have Medicaid. I’m going to keep posting this until people understand that when Medicaid gets cut *everyone* loses services.
May 12, 2025 at 4:18 PM
My daughter’s speech therapist went out of business because Medicaid reimbursement rates were too low. We do not have Medicaid. I’m going to keep posting this until people understand that when Medicaid gets cut *everyone* loses services.
Reposted by Julie Ostrander
please tell your letter-writers if you get the job/award!
May 12, 2025 at 9:10 PM
please tell your letter-writers if you get the job/award!
Reposted by Julie Ostrander
My new piece in @rollingstone.com : “Our democracy is made up of reciprocal ties between and among all of us, and AmeriCorps strengthens these ties. We will all feel the loss of AmeriCorps...and our democracy will pay the price.” www.rollingstone.com/politics/pol...
April 25, 2025 at 1:58 PM
My new piece in @rollingstone.com : “Our democracy is made up of reciprocal ties between and among all of us, and AmeriCorps strengthens these ties. We will all feel the loss of AmeriCorps...and our democracy will pay the price.” www.rollingstone.com/politics/pol...
Reposted by Julie Ostrander
The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23.
Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:
www.federalregister.gov/documents/20...
6/n
Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:
www.federalregister.gov/documents/20...
6/n
Improving Performance, Accountability and Responsiveness in the Civil Service
The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...
www.federalregister.gov
April 23, 2025 at 6:17 PM
The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23.
Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:
www.federalregister.gov/documents/20...
6/n
Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:
www.federalregister.gov/documents/20...
6/n
Reposted by Julie Ostrander
Please take a moment to read and sign this excellent letter. Over 3,500 signature so far!
Sen. Cory Booker urged us all to get in some good trouble. We're here to help with that. Sign our letter and find resources at wearehighered.org
docs.google.com/document/d/1...
docs.google.com/document/d/1...
Speaking Out for Democracy and US Higher Education
Speaking Out for Democracy and US Higher Education To add your name to this statement, go to https://bit.ly/DemocracyAndHigherEdSign if you are having trouble signing at the above linked form you can ...
docs.google.com
April 2, 2025 at 3:47 PM
Please take a moment to read and sign this excellent letter. Over 3,500 signature so far!
Reposted by Julie Ostrander
Analysis of Terminated NIH Grants with Word Clouds
First, using the titles of grants not to Columbia...
Gender and DEI predominate
First, using the titles of grants not to Columbia...
Gender and DEI predominate
March 29, 2025 at 11:02 PM
Analysis of Terminated NIH Grants with Word Clouds
First, using the titles of grants not to Columbia...
Gender and DEI predominate
First, using the titles of grants not to Columbia...
Gender and DEI predominate
Reposted by Julie Ostrander
Trump has cut the NIH budget by more than half in defiance of Congressionally mandated appropriations for the agency. No comparison historically, not even the Great Recession. This is clearly not legal and Congress needs to address it.
March 30, 2025 at 5:12 PM
Trump has cut the NIH budget by more than half in defiance of Congressionally mandated appropriations for the agency. No comparison historically, not even the Great Recession. This is clearly not legal and Congress needs to address it.
Reposted by Julie Ostrander
Review quality also maintained because rejection rate was similar among Fast & Fair vs conventional peer review...and Biology Open now publish all reviews, so readers can see for themselves
Can peer review be sped up ?
All manuscripts from a pilot study received reviews & first decisions within 7 business days.
The mean turnaround was 4.6 business days (n=20 manuscripts).
Review quality was maintained according to the academic editors.
www.biorxiv.org/content/10.1...
All manuscripts from a pilot study received reviews & first decisions within 7 business days.
The mean turnaround was 4.6 business days (n=20 manuscripts).
Review quality was maintained according to the academic editors.
www.biorxiv.org/content/10.1...
Fast & Fair peer review: a pilot study demonstrating feasibility of rapid, high-quality peer review in a biology journal
Traditional peer review is slow, often delayed by the time-consuming process of identifying reviewers and lengthy review turnaround times. This study tests the feasibility of the Fast & Fair peer revi...
www.biorxiv.org
March 25, 2025 at 1:38 PM
Review quality also maintained because rejection rate was similar among Fast & Fair vs conventional peer review...and Biology Open now publish all reviews, so readers can see for themselves
Reposted by Julie Ostrander
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
March 25, 2025 at 11:21 AM
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Reposted by Julie Ostrander
Providing every child access to a high quality education is the most important thing we can do to protect our future. An educated workforce drives the economy, scientific innovation and secures our countries place as a world leader. Eliminating the #doe will hurt all of us. #departmentofeducation
March 21, 2025 at 2:15 PM
Providing every child access to a high quality education is the most important thing we can do to protect our future. An educated workforce drives the economy, scientific innovation and secures our countries place as a world leader. Eliminating the #doe will hurt all of us. #departmentofeducation
Reposted by Julie Ostrander
The general vibe we are getting across #NIH institutes is deeply bleak — that the agency is nearly, if not already dead.
Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death.
1/
Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death.
1/
March 20, 2025 at 2:42 AM
The general vibe we are getting across #NIH institutes is deeply bleak — that the agency is nearly, if not already dead.
Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death.
1/
Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death.
1/
Reposted by Julie Ostrander
Still wrapping my head around 57% cut to CDMRP (cdmrp.health.mil) funding in CR.
CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates.
BEFORE the cut, the breast cancer program funded 3-5% of proposals.
What now?
CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates.
BEFORE the cut, the breast cancer program funded 3-5% of proposals.
What now?
cdmrp.health.mil
March 15, 2025 at 7:35 PM
Still wrapping my head around 57% cut to CDMRP (cdmrp.health.mil) funding in CR.
CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates.
BEFORE the cut, the breast cancer program funded 3-5% of proposals.
What now?
CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates.
BEFORE the cut, the breast cancer program funded 3-5% of proposals.
What now?
@amyklobuchar.com please don't vote for this CR as it is!!
If anyone is wondering why the republican's CR is worse than a government shutdown... The illegal spending cuts they have instituted in the last 2 months will become legal. There will be no recourse in the courts. Dems need to at least TRY and fight and negotiate! Call your SENATORS!
March 14, 2025 at 1:02 PM
@amyklobuchar.com please don't vote for this CR as it is!!
If anyone is wondering why the republican's CR is worse than a government shutdown... The illegal spending cuts they have instituted in the last 2 months will become legal. There will be no recourse in the courts. Dems need to at least TRY and fight and negotiate! Call your SENATORS!
March 14, 2025 at 1:01 PM
If anyone is wondering why the republican's CR is worse than a government shutdown... The illegal spending cuts they have instituted in the last 2 months will become legal. There will be no recourse in the courts. Dems need to at least TRY and fight and negotiate! Call your SENATORS!
Reposted by Julie Ostrander
The House Continuing Resolution budget “adjustments” for NIH are drastic. Here are some examples:
March 9, 2025 at 4:11 PM
The House Continuing Resolution budget “adjustments” for NIH are drastic. Here are some examples:
Reposted by Julie Ostrander
Please call your Congressmen today to tell them that you support children's cancer research and not to cut Dept of Defense CDMRP funding for cancer research. Vote No on the job-killing, kid-killing Continuing Resolution (CR) tomorrow. Also breast cancer, prostate cancer, Parkinson’s research, etc.
March 10, 2025 at 8:10 PM
Please call your Congressmen today to tell them that you support children's cancer research and not to cut Dept of Defense CDMRP funding for cancer research. Vote No on the job-killing, kid-killing Continuing Resolution (CR) tomorrow. Also breast cancer, prostate cancer, Parkinson’s research, etc.
Reposted by Julie Ostrander
Because one of the hats I wear is 'researcher with expertise in milk, lactation, & breastfeeding' I encounter folks who think breastfeeding is more important than vaccination...
Yes, I am about to launch a
Yes, I am about to launch a
a man in a suit and tie is saying `` chaos grenade '' while standing in an office .
Alt: a man in a suit and tie is saying `` chaos grenade '' while standing in an office pretending to throw said grenade.
media.tenor.com
March 9, 2025 at 6:36 PM
Because one of the hats I wear is 'researcher with expertise in milk, lactation, & breastfeeding' I encounter folks who think breastfeeding is more important than vaccination...
Yes, I am about to launch a
Yes, I am about to launch a
Stand up for Science at the MN Capital. Lots of great speakers talking about the impact of the current administration on scientific and medical research, public health, the environment, and DEI. @drnegillis.bsky.social @standupforscience.bsky.social
March 8, 2025 at 1:32 PM
Stand up for Science at the MN Capital. Lots of great speakers talking about the impact of the current administration on scientific and medical research, public health, the environment, and DEI. @drnegillis.bsky.social @standupforscience.bsky.social
@docfanning.bsky.social at UMN today telling us about his work on ER structure and Dickkopf-1. My personal favorite was the cameo appearance of PELP1. Great talk Sean!
March 6, 2025 at 4:14 AM
@docfanning.bsky.social at UMN today telling us about his work on ER structure and Dickkopf-1. My personal favorite was the cameo appearance of PELP1. Great talk Sean!