Joseph Luper Tsenum
josephtsenum.bsky.social
Joseph Luper Tsenum
@josephtsenum.bsky.social
PhD Researcher | Founder and CEO at Bio-PrecisionAI Health & NELIREF | Generative AI Drug Discovery | Explainable AI | Computational Biology/Chemistry | Bioinformatics | Biologics | Aptamers | Small Drug Molecules | ML | LLM | NLP
Reposted by Joseph Luper Tsenum
Digital biomarkers are advancing Alzheimer's diagnosis. A review of 431 studies and 86 AI models shows promise in areas like motor activity and speech analysis, with an average AUC of 0.887 for AD models. However, external validation and model calibration remain underutilized.
#MedSky #MLSky
Alzheimer’s disease digital biomarkers multidimensional landscape and AI model scoping review - npj Digital Medicine
npj Digital Medicine - Alzheimer’s disease digital biomarkers multidimensional landscape and AI model scoping review
www.nature.com
June 16, 2025 at 3:26 PM
AI Intern Job Posting

Job Tittle: AI for Drug Discovery Intern
 
Job Details: 
📍 Location: Remote
⏳ Duration: 3-6 months 
🗓 Start Date: Flexible
💰 Compensation: Paid
March 16, 2025 at 4:37 PM
March 16, 2025 at 4:35 PM
March 16, 2025 at 4:35 PM
Reposted by Joseph Luper Tsenum
The FDA's Digital Health Advisory Committee urges a total product life cycle approach for generative AI in medical devices, tackling regulatory challenges like output unpredictability and foundation model scope. 🩺🖥️
FDA taking the long view of generative AI in healthcare
The FDA’s fledgling Digital Health Advisory Committee (DHAC) only held its first meeting last week, but it has already committed its thinking to writing.
aiin.healthcare
November 27, 2024 at 4:49 PM
Reposted by Joseph Luper Tsenum
🧪 RhoFold+, a deep-learning tool, predicts RNA 3D structures in 0.14 seconds with high accuracy, tackling RNA flexibility and data scarcity. Applications: drug development, synthetic biology. 🧬🖥️
Deep learning revolutionizes RNA 3D structure prediction with RhoFold+
Researchers introduce RhoFold+, a groundbreaking deep learning model that predicts RNA 3D structures with unprecedented accuracy and efficiency, addressing critical challenges in structural biology.
www.news-medical.net
November 26, 2024 at 6:30 PM
Reposted by Joseph Luper Tsenum
My colleague Prof. Vlad Pena here at the @icrlondon.bsky.social has a job opening for a post-doctoral research fellow. The primary interest of the Pena lab is the structural biology (#cryoEM) of spliceosomal complexes. Interested? Please have a look:
jobs.icr.ac.uk/vacancies/10...
Postdoctoral Training Fellow - Mechanisms and Regulation of pre-mRNA Splicing in Chelsea | The Institute of Cancer Research
View details and apply for this Postdoctoral Training Fellow - Mechanisms and Regulation of pre-mRNA Splicing vacancy in Chelsea . Salary: Dependent on relevant Postdoctoral experience....
jobs.icr.ac.uk
November 15, 2024 at 4:00 PM
Reposted by Joseph Luper Tsenum
We just released 8 new data wrangling tutorials for biologists! sandbox.bio/community/da... 💻 🧬
Data and Text Processing
Command-line tutorials on data and text processing, by Francisco M. Couto.
sandbox.bio
November 15, 2024 at 5:28 PM
Reposted by Joseph Luper Tsenum
Sandbox.bio is a neat resource for learning data wrangling for bioinformatics! The tutorials are straightforward and I’ve definitely used it here and there to brush up on my CLI skills 🤩

Have tutorial ideas? Check out their GitHub to learn how to contribute to the project 👩🏽‍💻 💻 🧬
November 16, 2024 at 2:46 PM
Reposted by Joseph Luper Tsenum
AI is reshaping drug discovery and clinical trials, prompting the FDA to weigh new patient safety rules. Firms like PhaseV and BioPhy use AI for precise patient matching and trial diversity, enhancing efficiency but narrowing commercial reach. 🩺🖥️ #MLSky 💊
How A.I. Is Disrupting Pharma: The High-Stakes Race to Revolutionize Drug Discovery
While A.I. promises breakthroughs, industry leaders warn that transparency and patient safety must remain front and center.
observer.com
November 14, 2024 at 4:18 PM
Reposted by Joseph Luper Tsenum
This ability to bind to specific molecules makes aptamers very useful for a variety of applications, including biomarker discovery, drug development, and diagnostics.
November 27, 2023 at 1:42 PM