Joseph Kim
@joseph-kim.bsky.social
Postdoctoral Scientist in Aashish Manglik’s lab at UCSF: Biochemistry, cryo-EM, and pharmacology of GPCRs and transporters
PhD from University of Wisconsin-Madison: CLEM and Cryo-ET on neuronal cells
Triathlons, desserts, books, museums and video games
PhD from University of Wisconsin-Madison: CLEM and Cryo-ET on neuronal cells
Triathlons, desserts, books, museums and video games
Not to that degree as far as I can tell sadly, but my impression has been that whenever a group looks at a particular network/organelle within Chlamydomonas by mass spec or cultured under specific conditions, they find a lot:
www.sciencedirect.com/science/arti...
www.cell.com/cell/fulltex...
www.sciencedirect.com/science/arti...
www.cell.com/cell/fulltex...
A Spatial Interactome Reveals the Protein Organization of the Algal CO2-Concentrating Mechanism
Microscopy and proteomic analyses reveal three previously unknown layers of the pyrenoid,
the cellular organelle in algae responsible for one-third of global CO2 fixation
www.cell.com
January 19, 2025 at 5:40 AM
Not to that degree as far as I can tell sadly, but my impression has been that whenever a group looks at a particular network/organelle within Chlamydomonas by mass spec or cultured under specific conditions, they find a lot:
www.sciencedirect.com/science/arti...
www.cell.com/cell/fulltex...
www.sciencedirect.com/science/arti...
www.cell.com/cell/fulltex...
I disagree a little bit - if mass spec suggests anything, I think Chlamy is already highly dense, we're just not imagining what is possible based on current tools. I figure @cellarchlab.com is constantly finding new things every time they go through their data, especially when tools evolve.
January 13, 2025 at 8:35 PM
I disagree a little bit - if mass spec suggests anything, I think Chlamy is already highly dense, we're just not imagining what is possible based on current tools. I figure @cellarchlab.com is constantly finding new things every time they go through their data, especially when tools evolve.
That stereotypical arrangement will also be a huge advantage in making sure the sample was prepared correctly, something I don't think enough people are addressing when it comes to cellular cryo-ET work (blebbing, fragmentation, etc).
January 13, 2025 at 8:08 PM
That stereotypical arrangement will also be a huge advantage in making sure the sample was prepared correctly, something I don't think enough people are addressing when it comes to cellular cryo-ET work (blebbing, fragmentation, etc).
I (very loudly) wanted to stand up and shout 'THANK YOU' when he said that
January 11, 2025 at 11:16 PM
I (very loudly) wanted to stand up and shout 'THANK YOU' when he said that
Hi Cornelius, could you please add me as well? Many thanks!
January 10, 2025 at 1:34 PM
Hi Cornelius, could you please add me as well? Many thanks!
Reposted by Joseph Kim
The vagus nerve's prominent role in brain-gut, brain-immune system, brain-body interactions
Figure from www.scientificamerican.com/article/how-...
Figure from www.scientificamerican.com/article/how-...
December 19, 2024 at 2:17 PM
The vagus nerve's prominent role in brain-gut, brain-immune system, brain-body interactions
Figure from www.scientificamerican.com/article/how-...
Figure from www.scientificamerican.com/article/how-...
Hi Ute, I would like to be a part of this as well, thank you!
December 7, 2024 at 11:16 AM
Hi Ute, I would like to be a part of this as well, thank you!