Jordiet 🧫🧬
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jordiisevilla.bsky.social
Jordiet 🧫🧬
@jordiisevilla.bsky.social
Reposted by Jordiet 🧫🧬
Preprint on our new amr.watch tool from @thecgps.bsky.social - this incorporates and analyses genome data of key resistant pathogens from the public archives on an ongoing basis (every 4h) & presents the output via an interactive platform for monitoring AMR trends: www.biorxiv.org/content/10.1...
April 22, 2025 at 11:43 AM
Reposted by Jordiet 🧫🧬
I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...
Most bacterial gene families are biased toward specific chromosomal positions
The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...
www.science.org
April 10, 2025 at 7:43 PM
Reposted by Jordiet 🧫🧬
happy to share our new study! 🧪

while exploring how often #sars-cov-2 "repairs" deletions in BA.1, we found significant genome artifacts in GISAID 🤯 we compared with raw reads from ENA + tested the effects in vitro. turns out, data processing matters a lot 📉

check it out!! doi.org/10.1093/ve/v...
Genome data artifacts and functional studies of deletion repair in the BA.1 SARS-CoV-2 spike protein
Abstract. Mutations within the N-terminal domain (NTD) of the spike (S) protein are critical for the emergence of successful SARS-CoV-2 viral lineages. The
doi.org
April 3, 2025 at 3:11 PM
Reposted by Jordiet 🧫🧬
100 years with the Lotka-Volterra equation... let's celebrate!
January 29, 2025 at 7:22 AM
Reposted by Jordiet 🧫🧬
Interested in predicting AMR in bacteria? We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. With @nwheeler443.bsky.social and former PhD student Yanying Yu. 🦠🧫🧬🖥️🧪

www.biorxiv.org/content/10.1...
Biased sampling confounds machine learning prediction of antimicrobial resistance
Antimicrobial resistance (AMR) poses a growing threat to human health. Increasingly, genome sequencing is being applied for the surveillance of bacterial pathogens, producing a wealth of data to train...
www.biorxiv.org
January 17, 2025 at 10:08 PM
Reposted by Jordiet 🧫🧬
Sharing three fully funded PhD opportunities to join my lab at Queen’s to work on topics spanning bacterial pathogens, antibiotic resistance, microbial interactions, & mobile genetic elements 🦠. Closing dates in January and February, and open to international candidates 🌍 Projects detailed below ⬇️
December 30, 2024 at 2:27 PM
Reposted by Jordiet 🧫🧬
📣Our latest paper is out now in mSystems: Not quite as it may seem - investigating #plasmid diversity and evolution in #Klebsiella pneumoniae at a single institution over time. A short thread 🧵 @zaminiqbal.bsky.social
January 14, 2025 at 2:20 PM