6/6 From what I've seen, many institutions have also noticed this shift and are focusing resources on these technological developments for the sake of developing treatments and undertaking research that is heavily transnational in lieu of basic science.

5/6 So what will future Nobels look like? It seems to me that, eventually, the age of discovery will end and be replaced with an age of innovation in which much of the most impactful research will be focused on the development of new technologies rather than discovery of a new protein or cell type

4/6 In addition, we now integrate multiple systems within each research project (e.g. neuro-immune, cancer-metabolism, cancer-immunology, etc.) and are studying interactions between cell types and, again, context-dependent functions, which do not generally get awarded the Nobel.

3/6 With the current methodologies, much of the research is focused on determining how different cell states and context-dependent functions of cells impact health, but these types of discoveries, although important, do not usually lead to paradigm shifting advances in the field warranting the Nobel

2/6 Today, with the spread of omics technologies, we have essentially already established what cells exist and have an idea of their overall functions. We will no longer be able to look at a disease, or a classification of diseases, and pin the blame on a new cell type. Problems are more complex.