Jo Poole
@jopodr.bsky.social
Anaesthesia. ICM. Mitochondria. Evolution. Once slept in a museum.
Anyone know if NHS pensions are tax deductible in terms of adjusted net income?
August 5, 2025 at 12:49 PM
Anyone know if NHS pensions are tax deductible in terms of adjusted net income?
Reposted by Jo Poole
🧵1/15 Delighted to share our study on the naked mole-rat (NMR): a mammal with bizarre thermal biology, notorious longevity, and cancer resistance. But how do NMRs maintain (or fail to maintain) their body temperature? Our latest work digs deep! #ThermalBiology #Thermogenesis
July 28, 2025 at 2:23 PM
🧵1/15 Delighted to share our study on the naked mole-rat (NMR): a mammal with bizarre thermal biology, notorious longevity, and cancer resistance. But how do NMRs maintain (or fail to maintain) their body temperature? Our latest work digs deep! #ThermalBiology #Thermogenesis
Interesting biomarker for 24 hour and 28 day mortality in critically ill patients (reflects metalloproteinase tissue damage and angiotensin II activity). AUC 0.83 for 24 hour. Interestingly subgroup with elevated biomarker & ACEi use higher mortality ccforum.biomedcentral.com/articles/10.... #emimcc
Value of cDPP3 as a short-term prognostic biomarker in all-comers critically ill patients in the emergency department - Critical Care
ccforum.biomedcentral.com
July 25, 2025 at 10:29 AM
Interesting biomarker for 24 hour and 28 day mortality in critically ill patients (reflects metalloproteinase tissue damage and angiotensin II activity). AUC 0.83 for 24 hour. Interestingly subgroup with elevated biomarker & ACEi use higher mortality ccforum.biomedcentral.com/articles/10.... #emimcc
Reposted by Jo Poole
What if something quick and free could cut your heart attack risk by 34%? Getting a flu vaccine each year is linked to a 34% lower risk of major cardiovascular events. jamanetwork.com/journals/jam...
Influenza Vaccination and Cardiovascular Risk
This meta-analysis updates a previous meta-analysis examining the association of seasonal influenza vaccination with prevention of adverse cardiovascular events for a new large clinical trial.
jamanetwork.com
July 4, 2025 at 2:26 PM
What if something quick and free could cut your heart attack risk by 34%? Getting a flu vaccine each year is linked to a 34% lower risk of major cardiovascular events. jamanetwork.com/journals/jam...
Reposted by Jo Poole
Use of Intralipid in a Propranolol/Quetiapine induced cardiac arrest - our poster today at #SOA25
Evidence for lipid rescue is (and will likely remain) limited, but it really was an inspiring and uplifting case to have been a part of - ROSC after 76 mins CPR and an excellent neurological outcome.
Evidence for lipid rescue is (and will likely remain) limited, but it really was an inspiring and uplifting case to have been a part of - ROSC after 76 mins CPR and an excellent neurological outcome.
July 2, 2025 at 9:13 PM
Use of Intralipid in a Propranolol/Quetiapine induced cardiac arrest - our poster today at #SOA25
Evidence for lipid rescue is (and will likely remain) limited, but it really was an inspiring and uplifting case to have been a part of - ROSC after 76 mins CPR and an excellent neurological outcome.
Evidence for lipid rescue is (and will likely remain) limited, but it really was an inspiring and uplifting case to have been a part of - ROSC after 76 mins CPR and an excellent neurological outcome.
Reposted by Jo Poole
My family had a recent experience of hospital care & we saw effect of this type of taskification of care. Pointless delays, miscommunication, unnecessary referrals etc. No one had the patient at the core of their thinking as they did their bit of the job - result was real anguish
"For too long, we have trained ‘to role’ - often requiring individuals to complete years of training - when many tasks can be carried out with good supervision."
For your reading pleasure the 10 year NHS plan: www.gov.uk/government/p...
July 3, 2025 at 2:09 PM
My family had a recent experience of hospital care & we saw effect of this type of taskification of care. Pointless delays, miscommunication, unnecessary referrals etc. No one had the patient at the core of their thinking as they did their bit of the job - result was real anguish
Reposted by Jo Poole
These cuts come as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.
In May, RFK Jr threatened to bar government scientists from publishing in top medical journals.
And several journals received letters in April from DOJ alleging political bias in the research they publish.
In May, RFK Jr threatened to bar government scientists from publishing in top medical journals.
And several journals received letters in April from DOJ alleging political bias in the research they publish.
June 30, 2025 at 8:57 PM
These cuts come as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.
In May, RFK Jr threatened to bar government scientists from publishing in top medical journals.
And several journals received letters in April from DOJ alleging political bias in the research they publish.
In May, RFK Jr threatened to bar government scientists from publishing in top medical journals.
And several journals received letters in April from DOJ alleging political bias in the research they publish.
Just lmao
Trump team axes contracts with publishing giant Springer Nature
At first, NIH told me its contracts with SN were active and that they help “advance scientific discovery”.
Hours later, HHS said the opposite: "Precious taxpayer dollars should not be used on unused subscriptions to junk science.”
At first, NIH told me its contracts with SN were active and that they help “advance scientific discovery”.
Hours later, HHS said the opposite: "Precious taxpayer dollars should not be used on unused subscriptions to junk science.”
Trump team axes contracts with publishing giant Springer Nature
The action comes as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.
www.nature.com
July 1, 2025 at 4:54 PM
Just lmao
Reposted by Jo Poole
Once again, this is why we cannot ask pregnant trainees / early career faculty to attend scientific & medical conferences in states that outlaw abortion, and hence why we absolutely must not hold conferences in these states
NEW: More women have nearly bled to death during miscarriage under Texas’ abortion ban.
Experts say the trend paints a troubling picture of the harms of unnecessary delays in care. “This is striking,” one doctor said. “The trend is very clear.”
Experts say the trend paints a troubling picture of the harms of unnecessary delays in care. “This is striking,” one doctor said. “The trend is very clear.”
A “Striking” Trend: After Texas Banned Abortion, More Women Nearly Bled to Death During Miscarriage
A new ProPublica data analysis adds to the mounting evidence that abortion bans have made the common experience of first-trimester miscarriage far more dangerous.
www.propublica.org
July 1, 2025 at 2:36 PM
Once again, this is why we cannot ask pregnant trainees / early career faculty to attend scientific & medical conferences in states that outlaw abortion, and hence why we absolutely must not hold conferences in these states
Reposted by Jo Poole
July 1, 2025 at 9:28 AM
Reposted by Jo Poole
Our next session is on the recent excellent @ncepod.bsky.social report on rehabilitation after critical illness
This can be read here ncepod.org.uk/2025icur.html
Spoiler alert: we have much to improve on
#soa25
This can be read here ncepod.org.uk/2025icur.html
Spoiler alert: we have much to improve on
#soa25
NCEPOD - Rehabilitation following critical illness: (2025)
The National Confidential Enquiry into Patient Outcome and Death (NCEPOD) reviews clinical practice and identifies potentially remediable factors in the practice of patient care.
ncepod.org.uk
July 1, 2025 at 10:18 AM
Our next session is on the recent excellent @ncepod.bsky.social report on rehabilitation after critical illness
This can be read here ncepod.org.uk/2025icur.html
Spoiler alert: we have much to improve on
#soa25
This can be read here ncepod.org.uk/2025icur.html
Spoiler alert: we have much to improve on
#soa25
Reposted by Jo Poole
Honestly could have fed Prof Rockwood Questions for an hour!what a fantastic and relevant session on Frailty #SOA25
Really looking forward to this opening plenary - Prof Rockwood himself!
Being literate in frailty is every clinician’s business, but it is especially our business….
The @ics-updates.bsky.social flagship conference SOA is in Birmingham in July, online and in person 📟⚕️
Being literate in frailty is every clinician’s business, but it is especially our business….
The @ics-updates.bsky.social flagship conference SOA is in Birmingham in July, online and in person 📟⚕️
July 1, 2025 at 10:31 AM
Honestly could have fed Prof Rockwood Questions for an hour!what a fantastic and relevant session on Frailty #SOA25
These are war crimes, missile attacks in areas full of defenceless civilians and children are pathetic - why is there so much inaction on the atrocities being committed by the IDF? We wouldn’t tolerate other nations doing this? www.theguardian.com/world/2025/j...
Witnesses describe grim aftermath of Israeli strike on busy Gaza cafe
Women, children and elderly people among at least 24 killed by attack that turned beach spot into scene of carnage
www.theguardian.com
July 1, 2025 at 10:36 AM
These are war crimes, missile attacks in areas full of defenceless civilians and children are pathetic - why is there so much inaction on the atrocities being committed by the IDF? We wouldn’t tolerate other nations doing this? www.theguardian.com/world/2025/j...
Reposted by Jo Poole
the volume of an ellipsoid is ABC/2
so if a patient is in hemorrhagic shock with an 3x4x5 cm hematoma in their abdomen, the hematoma *cannot* explain their hemorrhagic shock (estimated 30 cc volume)
keep looking for the source of bleeding (which statistically is likely to be a GI bleed) #EMIMCC
so if a patient is in hemorrhagic shock with an 3x4x5 cm hematoma in their abdomen, the hematoma *cannot* explain their hemorrhagic shock (estimated 30 cc volume)
keep looking for the source of bleeding (which statistically is likely to be a GI bleed) #EMIMCC
June 28, 2025 at 2:03 PM
the volume of an ellipsoid is ABC/2
so if a patient is in hemorrhagic shock with an 3x4x5 cm hematoma in their abdomen, the hematoma *cannot* explain their hemorrhagic shock (estimated 30 cc volume)
keep looking for the source of bleeding (which statistically is likely to be a GI bleed) #EMIMCC
so if a patient is in hemorrhagic shock with an 3x4x5 cm hematoma in their abdomen, the hematoma *cannot* explain their hemorrhagic shock (estimated 30 cc volume)
keep looking for the source of bleeding (which statistically is likely to be a GI bleed) #EMIMCC
Reposted by Jo Poole
If you read one thing today, read this.
“On Not Betraying Our Trainees, Especially Now”
I won an Extraordinary Achievement Award from the Critical Care Assembly last month
The @atscommunity.bsky.social premier journal @atsblueeditor.bsky.social TODAY published the remarks I made on that occasion
www.atsjournals.org/doi/10.1164/...
I won an Extraordinary Achievement Award from the Critical Care Assembly last month
The @atscommunity.bsky.social premier journal @atsblueeditor.bsky.social TODAY published the remarks I made on that occasion
www.atsjournals.org/doi/10.1164/...
On Not Betraying Our Trainees, Especially Now | American Journal of Respiratory and Critical Care Medicine | Articles in Press
www.atsjournals.org
June 27, 2025 at 11:57 AM
If you read one thing today, read this.
Reposted by Jo Poole
I've been diving into evidence on Covid vax in pregnancy & sorting through misinformation, incl the claim Pfizer never reported on its pregnancy trial. I ended up relieved!
Check out studies in >1.5 million vaxed pregnant participants in my latest @plos.org absolutelymaybe.plos.org/2025/06/27/d...
Check out studies in >1.5 million vaxed pregnant participants in my latest @plos.org absolutelymaybe.plos.org/2025/06/27/d...
Digging Into the Evidence on Covid Vaccines in Pregnancy - Absolutely Maybe
Decision-making about drugs in pregnancy can be very difficult. Our illogical aversion to clinical trials in pregnancy means people making particularly complex…
absolutelymaybe.plos.org
June 27, 2025 at 6:45 AM
I've been diving into evidence on Covid vax in pregnancy & sorting through misinformation, incl the claim Pfizer never reported on its pregnancy trial. I ended up relieved!
Check out studies in >1.5 million vaxed pregnant participants in my latest @plos.org absolutelymaybe.plos.org/2025/06/27/d...
Check out studies in >1.5 million vaxed pregnant participants in my latest @plos.org absolutelymaybe.plos.org/2025/06/27/d...
#FICM safety bulletin www.ficm.ac.uk/sites/ficm/f...
www.ficm.ac.uk
June 26, 2025 at 9:58 AM
#FICM safety bulletin www.ficm.ac.uk/sites/ficm/f...
Reposted by Jo Poole
expert reaction to a Wellcome announcement on a new Synthetic Human Genome research project (SynHG)
www.sciencemediacentre.org/expert-react...
www.sciencemediacentre.org/expert-react...
expert reaction to a Wellcome announcement on a new Synthetic Human Genome research project (SynHG) | Science Media Centre
www.sciencemediacentre.org
June 26, 2025 at 9:33 AM
expert reaction to a Wellcome announcement on a new Synthetic Human Genome research project (SynHG)
www.sciencemediacentre.org/expert-react...
www.sciencemediacentre.org/expert-react...
The vaccine situation in US government is depressing. Watching a successful (of course imperfect) nation disassemble itself is eerie. What has brought that into being and how do we prevent that in Europe?
June 26, 2025 at 7:44 AM
The vaccine situation in US government is depressing. Watching a successful (of course imperfect) nation disassemble itself is eerie. What has brought that into being and how do we prevent that in Europe?
Reposted by Jo Poole
Prework walk near #PapworthWood
Sound track = reed warbler, sedge warbler, wren, chiffchaff, greater whitethroat
Sound track = reed warbler, sedge warbler, wren, chiffchaff, greater whitethroat
June 26, 2025 at 6:58 AM
Prework walk near #PapworthWood
Sound track = reed warbler, sedge warbler, wren, chiffchaff, greater whitethroat
Sound track = reed warbler, sedge warbler, wren, chiffchaff, greater whitethroat
We actually don’t have lots of side effect data on these meds and their availability from online pharmacy with few safety checks is already contributing to overdoses and complications in the non obese in my region #medsky #ansky
Worryingly this report also came out today citing issues with acute pancreatitis experienced by some patients
Hundreds of weight loss and diabetes jab users report pancreas problems
UK health officials launch study into side-effects of weight loss drugs after increased reports of acute pancreatitis
www.theguardian.com
June 26, 2025 at 7:39 AM