Jonathan G. Stine, MD MSc, FACP
@jonathanstinemd.bsky.social
Global Clinical Program Lead – Late CVRM @AstraZeneca | Clinical Professor of Medicine @PennState | #MASH researcher | Tackling liver health through science & lifestyle | #LiverSky #MASLD #run #lift #yoga #snowboard #read #garden | views my own
The muscle–adipose–liver axis is critical, yet underrecognized, in #MASLD.
Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis.
Its time to standardize definitions and intervene early:
link.springer.com/article/10.1...
Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis.
Its time to standardize definitions and intervene early:
link.springer.com/article/10.1...
June 1, 2025 at 8:57 PM
The muscle–adipose–liver axis is critical, yet underrecognized, in #MASLD.
Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis.
Its time to standardize definitions and intervene early:
link.springer.com/article/10.1...
Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis.
Its time to standardize definitions and intervene early:
link.springer.com/article/10.1...
#Exercise may protect the liver by blocking ferroptosis, a key cell death pathway in #MASLD. 🏃♀️🧬
New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence
pubmed.ncbi.nlm.nih.gov/40206477/
New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence
pubmed.ncbi.nlm.nih.gov/40206477/
April 16, 2025 at 12:32 PM
#Exercise may protect the liver by blocking ferroptosis, a key cell death pathway in #MASLD. 🏃♀️🧬
New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence
pubmed.ncbi.nlm.nih.gov/40206477/
New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence
pubmed.ncbi.nlm.nih.gov/40206477/
Ok, I couldn't resist this trend any longer... I had to have ChatGPT make my action figure based on my bio and here is what it generated 😂 😂 😂
April 14, 2025 at 4:17 PM
Ok, I couldn't resist this trend any longer... I had to have ChatGPT make my action figure based on my bio and here is what it generated 😂 😂 😂
Happy #InternationalDayofWomenandGirlsinScience!
🌟 Today, we celebrate the brilliant and innovative women pushing boundaries in research.
A special shoutout to the incredible women in the Stine Lab, whose talent and dedication drive scientific discovery daily!
#WomenInScience
🌟 Today, we celebrate the brilliant and innovative women pushing boundaries in research.
A special shoutout to the incredible women in the Stine Lab, whose talent and dedication drive scientific discovery daily!
#WomenInScience
February 11, 2025 at 7:00 PM
Happy #InternationalDayofWomenandGirlsinScience!
🌟 Today, we celebrate the brilliant and innovative women pushing boundaries in research.
A special shoutout to the incredible women in the Stine Lab, whose talent and dedication drive scientific discovery daily!
#WomenInScience
🌟 Today, we celebrate the brilliant and innovative women pushing boundaries in research.
A special shoutout to the incredible women in the Stine Lab, whose talent and dedication drive scientific discovery daily!
#WomenInScience
Our multidisciplinary care model for adults with fibrotic #MASH leads to clinically meaningful improvements in #liver and metabolic health:
🔹 Individualized Rx plans
🔹 Lifestyle intervention + pharmacotherapy
🔹 Inclusion of EPs, obesity medicine
journals.lww.com/hepcomm/page...
🔹 Individualized Rx plans
🔹 Lifestyle intervention + pharmacotherapy
🔹 Inclusion of EPs, obesity medicine
journals.lww.com/hepcomm/page...
February 3, 2025 at 9:46 PM
Our multidisciplinary care model for adults with fibrotic #MASH leads to clinically meaningful improvements in #liver and metabolic health:
🔹 Individualized Rx plans
🔹 Lifestyle intervention + pharmacotherapy
🔹 Inclusion of EPs, obesity medicine
journals.lww.com/hepcomm/page...
🔹 Individualized Rx plans
🔹 Lifestyle intervention + pharmacotherapy
🔹 Inclusion of EPs, obesity medicine
journals.lww.com/hepcomm/page...
#MASLD Health Tip of the Day:
Enjoy your coffee!
Drinking 3 cups of black coffee daily can reduce liver inflammation and support liver health, and has been linked to lower fibrosis
A little cream or sugar is okay, but black coffee offers the most benefit. ☕ #LiverHealth
Enjoy your coffee!
Drinking 3 cups of black coffee daily can reduce liver inflammation and support liver health, and has been linked to lower fibrosis
A little cream or sugar is okay, but black coffee offers the most benefit. ☕ #LiverHealth
January 31, 2025 at 12:23 PM
#MASLD Health Tip of the Day:
Enjoy your coffee!
Drinking 3 cups of black coffee daily can reduce liver inflammation and support liver health, and has been linked to lower fibrosis
A little cream or sugar is okay, but black coffee offers the most benefit. ☕ #LiverHealth
Enjoy your coffee!
Drinking 3 cups of black coffee daily can reduce liver inflammation and support liver health, and has been linked to lower fibrosis
A little cream or sugar is okay, but black coffee offers the most benefit. ☕ #LiverHealth
#MASLD Tip of the Day!
Be Active: You don’t need to be a gym rat to protect your liver!
Walking, cycling, or any moderate activity helps.
Aim for 150 min/wk of moderate-intensity aerobic activity. How intense is that? You should be able to talk but not sing while moving
Be Active: You don’t need to be a gym rat to protect your liver!
Walking, cycling, or any moderate activity helps.
Aim for 150 min/wk of moderate-intensity aerobic activity. How intense is that? You should be able to talk but not sing while moving
January 30, 2025 at 11:20 AM
#MASLD Tip of the Day!
Be Active: You don’t need to be a gym rat to protect your liver!
Walking, cycling, or any moderate activity helps.
Aim for 150 min/wk of moderate-intensity aerobic activity. How intense is that? You should be able to talk but not sing while moving
Be Active: You don’t need to be a gym rat to protect your liver!
Walking, cycling, or any moderate activity helps.
Aim for 150 min/wk of moderate-intensity aerobic activity. How intense is that? You should be able to talk but not sing while moving
Grateful to the Hepatic Hope Foundation for supporting our #research on #exercise & lifestyle interventions for liver disease! Their funding fuels our work exploring how tailored exercise may slow biological aging in #MASLD
www.hepatichope.org/research-upd...
www.hepatichope.org/research-upd...
January 29, 2025 at 9:38 PM
Grateful to the Hepatic Hope Foundation for supporting our #research on #exercise & lifestyle interventions for liver disease! Their funding fuels our work exploring how tailored exercise may slow biological aging in #MASLD
www.hepatichope.org/research-upd...
www.hepatichope.org/research-upd...
Healthy #MASLD Tip of the Day:
Eat a Mediterranean-style diet!
Load up on fruits, veggies, whole grains, and lean proteins.
Foods like broccoli, spinach, and berries are rich in antioxidants that protect your liver.
Limit processed foods, added sugars, and saturated fats!
Eat a Mediterranean-style diet!
Load up on fruits, veggies, whole grains, and lean proteins.
Foods like broccoli, spinach, and berries are rich in antioxidants that protect your liver.
Limit processed foods, added sugars, and saturated fats!
January 29, 2025 at 2:24 PM
Healthy #MASLD Tip of the Day:
Eat a Mediterranean-style diet!
Load up on fruits, veggies, whole grains, and lean proteins.
Foods like broccoli, spinach, and berries are rich in antioxidants that protect your liver.
Limit processed foods, added sugars, and saturated fats!
Eat a Mediterranean-style diet!
Load up on fruits, veggies, whole grains, and lean proteins.
Foods like broccoli, spinach, and berries are rich in antioxidants that protect your liver.
Limit processed foods, added sugars, and saturated fats!
Healthy #liver lifestyle tip of the day for those living with #MASLD: Small, consistent steps can lead to big results!
For example, adding just 2,500 steps to your daily routine can reduce your risk of liver disease progression by 20%.
Start where you are, and build from there.
For example, adding just 2,500 steps to your daily routine can reduce your risk of liver disease progression by 20%.
Start where you are, and build from there.
January 28, 2025 at 5:48 PM
In challenging times, little reminders about the impact you are making go a long way.
I was incredibly touched a patient of mine took the time to draw two of my favorite things and give this to me!
Makes me think the #snowboarding #liver should be our new lab logo
I was incredibly touched a patient of mine took the time to draw two of my favorite things and give this to me!
Makes me think the #snowboarding #liver should be our new lab logo
January 28, 2025 at 3:46 PM
In challenging times, little reminders about the impact you are making go a long way.
I was incredibly touched a patient of mine took the time to draw two of my favorite things and give this to me!
Makes me think the #snowboarding #liver should be our new lab logo
I was incredibly touched a patient of mine took the time to draw two of my favorite things and give this to me!
Makes me think the #snowboarding #liver should be our new lab logo
On call this weekend and reppin’ The Birds!
Fly 🦅 Fly! Super Bowl here we come!
Fly 🦅 Fly! Super Bowl here we come!
January 26, 2025 at 2:37 PM
On call this weekend and reppin’ The Birds!
Fly 🦅 Fly! Super Bowl here we come!
Fly 🦅 Fly! Super Bowl here we come!
Happy Holidays from our team to yours! 🎄✨ Wishing you and your loved ones peace, joy, and good health this season. Let’s continue making strides in #liver health and wellness together in 2025. Cheers to a bright and active new year! – #Hepatology #HappyHolidays
December 24, 2024 at 2:46 PM
Happy Holidays from our team to yours! 🎄✨ Wishing you and your loved ones peace, joy, and good health this season. Let’s continue making strides in #liver health and wellness together in 2025. Cheers to a bright and active new year! – #Hepatology #HappyHolidays
Huge thanks to Jefferson and Einstein Hepatolgoy group for having me speak today! What a great year in #MASLD to reflect on! Looking forward to all that 2025 brings to our patients!
December 14, 2024 at 11:41 PM
Huge thanks to Jefferson and Einstein Hepatolgoy group for having me speak today! What a great year in #MASLD to reflect on! Looking forward to all that 2025 brings to our patients!
Huge thanks to @amcollegegastro.bsky.social for having me today to discuss all things #exercise and #MASLD #MASH related!
Such great Q from the audience- you have inspired new ideas that are bouncing around my head! Thank you!!!
Such great Q from the audience- you have inspired new ideas that are bouncing around my head! Thank you!!!
December 5, 2024 at 6:03 PM
Huge thanks to @amcollegegastro.bsky.social for having me today to discuss all things #exercise and #MASLD #MASH related!
Such great Q from the audience- you have inspired new ideas that are bouncing around my head! Thank you!!!
Such great Q from the audience- you have inspired new ideas that are bouncing around my head! Thank you!!!
Even though she was tricked by Hades, 🍎 Persephone was onto something for #MASLD!
New study finds pomegranate peel extract + a low-calorie diet improves:
✅ Liver enzymes
✅ Lipids
✅ Inflammation
Queen of the Underworld knew her superfoods. 🏺✨
pubmed.ncbi.nlm.nih.gov/39608758/
New study finds pomegranate peel extract + a low-calorie diet improves:
✅ Liver enzymes
✅ Lipids
✅ Inflammation
Queen of the Underworld knew her superfoods. 🏺✨
pubmed.ncbi.nlm.nih.gov/39608758/
December 4, 2024 at 5:32 PM
Even though she was tricked by Hades, 🍎 Persephone was onto something for #MASLD!
New study finds pomegranate peel extract + a low-calorie diet improves:
✅ Liver enzymes
✅ Lipids
✅ Inflammation
Queen of the Underworld knew her superfoods. 🏺✨
pubmed.ncbi.nlm.nih.gov/39608758/
New study finds pomegranate peel extract + a low-calorie diet improves:
✅ Liver enzymes
✅ Lipids
✅ Inflammation
Queen of the Underworld knew her superfoods. 🏺✨
pubmed.ncbi.nlm.nih.gov/39608758/
🔥🆙 to scope in my Eagles scrub cap after Saquon’s performance last night! Go birds!
November 25, 2024 at 6:46 PM
🔥🆙 to scope in my Eagles scrub cap after Saquon’s performance last night! Go birds!
Shira Zelber-Sagi and I can’t wait to have lunch and a friendly fireside-chat type discussion with all who registered for AASLD #TLM24 MTE session about #lifestyle #diet #exercise #MASLD
November 18, 2024 at 8:20 PM
Shira Zelber-Sagi and I can’t wait to have lunch and a friendly fireside-chat type discussion with all who registered for AASLD #TLM24 MTE session about #lifestyle #diet #exercise #MASLD
November 15, 2024 at 7:29 PM
