Jonathan Pollack
@jonathanpollack.bsky.social
Photographer, jack of all trades | #IgANephropathy patient | Amateur researcher | #STL
Key points:
+ Stable eGFR at week 96 (+2.5 mL/min/1.73 m²)
+ Gd-IgA1 production down 50% at week 96
+ Proteinuria (UPCR) reduced by 55.2% at week 96
This is at week 96, 18 *months* after treatment was discontinued at week 24. #NephSky #KidneyWk #IgAN #IgANephropathy
+ Stable eGFR at week 96 (+2.5 mL/min/1.73 m²)
+ Gd-IgA1 production down 50% at week 96
+ Proteinuria (UPCR) reduced by 55.2% at week 96
This is at week 96, 18 *months* after treatment was discontinued at week 24. #NephSky #KidneyWk #IgAN #IgANephropathy
November 11, 2025 at 4:34 PM
Key points:
+ Stable eGFR at week 96 (+2.5 mL/min/1.73 m²)
+ Gd-IgA1 production down 50% at week 96
+ Proteinuria (UPCR) reduced by 55.2% at week 96
This is at week 96, 18 *months* after treatment was discontinued at week 24. #NephSky #KidneyWk #IgAN #IgANephropathy
+ Stable eGFR at week 96 (+2.5 mL/min/1.73 m²)
+ Gd-IgA1 production down 50% at week 96
+ Proteinuria (UPCR) reduced by 55.2% at week 96
This is at week 96, 18 *months* after treatment was discontinued at week 24. #NephSky #KidneyWk #IgAN #IgANephropathy
Where's the kale salad?
November 10, 2025 at 2:55 PM
Where's the kale salad?
Part of my complete [hour prior to] breakfast.
November 10, 2025 at 1:45 PM
Part of my complete [hour prior to] breakfast.
Guessing that if this is successful, each one would go to a patient in need, the pig will be euthanized and its biomarkers studied, and the bacon goes to waste.
November 9, 2025 at 11:16 PM
Guessing that if this is successful, each one would go to a patient in need, the pig will be euthanized and its biomarkers studied, and the bacon goes to waste.
I'm always available!
November 9, 2025 at 8:13 PM
I'm always available!
Maybe the care team gets the pork? These decisions are way above my pay grade and authority.
November 9, 2025 at 1:58 PM
Maybe the care team gets the pork? These decisions are way above my pay grade and authority.
See also bsky.app/profile/kidn... #KidneyWk
November 8, 2025 at 6:27 PM
See also bsky.app/profile/kidn... #KidneyWk
Plus there's telitacicept, though that trial was only in China. Poveticicept comes this afternoon. So not only the question of BAFF+APRIL vs. APRIL alone, but now which variety works best?
November 8, 2025 at 5:39 PM
Plus there's telitacicept, though that trial was only in China. Poveticicept comes this afternoon. So not only the question of BAFF+APRIL vs. APRIL alone, but now which variety works best?
Yet another one...
"The key secondary end point of annualized eGFR slope estimated over 24 months currently remains blinded to preserve ongoing trial integrity and is not reported here."
"The key secondary end point of annualized eGFR slope estimated over 24 months currently remains blinded to preserve ongoing trial integrity and is not reported here."
November 8, 2025 at 5:36 PM
Yet another one...
"The key secondary end point of annualized eGFR slope estimated over 24 months currently remains blinded to preserve ongoing trial integrity and is not reported here."
"The key secondary end point of annualized eGFR slope estimated over 24 months currently remains blinded to preserve ongoing trial integrity and is not reported here."
Sounds beneficial even without albuminaria and with low eGFR. I'm selfishly extra curious how SGLT2 inhibitors stack with other therapeutics in patients who are in remission and with stable eGFR.
November 8, 2025 at 12:14 AM
Sounds beneficial even without albuminaria and with low eGFR. I'm selfishly extra curious how SGLT2 inhibitors stack with other therapeutics in patients who are in remission and with stable eGFR.
Sodium is a great flavor substitute.
November 7, 2025 at 1:37 AM
Sodium is a great flavor substitute.