jogoall.bsky.social
@jogoall.bsky.social
Reposted
Out today — results of the QUASAR phase 3 trial of guselkumab in patients with moderately to severely active ulcerative colitis

@thelancet.bsky.social

www.thelancet.com/journals/lan...

#GastroSky #IBDSky #MedSky
Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies
Guselkumab was effective and safe as induction and maintenance therapy in patients with moderately to severely active ulcerative colitis.
www.thelancet.com
December 18, 2024 at 6:58 AM
Reposted
The QUASAR trial- guselkumab vs placebo in mod-severe UC

1️⃣Induction 200mg IV (0,4,8) or placebo

📗Maintenance 200mg SC q4w, 100mg SC q8w or placebo
Guselkumab better than placebo in all the outcomes

@thelancet.bsky.social

www.thelancet.com/journals/lan...
December 18, 2024 at 6:40 AM
Reposted
Portugal é o país onde menos crianças passam fome nas escolas.

Algumas coisas boas sobre educação em Portugal (e outras más) com o José Maria Pimentel para o 45 Graus. Falámos sobre educação, pobreza, desigualdade, classes sociais, professores.

Podem ouvir aqui:

👉 open.spotify.com/episode/0F63...
November 24, 2024 at 11:10 PM
Reposted
A ouvir o 45o com o @miguelherdade.bsky.social . Ouçam que vale sempre a pena ouvir o Miguel Herdade.
November 25, 2024 at 7:04 PM
Reposted
A strict gluten-free diet is the only effective means to manage coeliac disease, but comes with substantial challenges; there is a clear need for novel therapies.

New research explores the potential of IMU-856, which aims to restore intestinal barrier function.

buff.ly/4f3APpC

#GastroSky #MedSky
Rob Brierley on LinkedIn: #gastroenterology #celiacdisease #coeliacdisease
Coeliac disease affects an estimated 1.4% of the global population. A strict gluten-free diet is, at present, the only effective means to manage the disease…
www.linkedin.com
December 5, 2024 at 1:25 PM
Reposted
🎉The latest IBD-Ell newsletter is out!
- New trials added 🌟We've far surpassed 400 summarized trials🌟
- New guidelines
- New cheat sheet with lymphocyte trafficking and anti-integrins
Thanks for following along! www.ibd-eii.com
Subscribe for free anytime 📩
#IBD
November 27, 2024 at 7:31 AM
Reposted
This JAMA Insights discusses ovarian aging and provides strategies to address infertility due to ovarian aging.

ja.ma/414eoxu
November 26, 2024 at 8:12 PM
Reposted
Choose 20 books that have stayed with you or influenced you.

One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

Day 3

#booksky
💙📚
#books
#bookchallenge
November 22, 2024 at 2:47 AM
Reposted
Choose 20 books that have stayed with you or influenced you.

One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

Day 4

#booksky
💙📚
#books
#bookchallenge
November 23, 2024 at 12:34 AM
Reposted
Choose 20 books that have stayed with you or influenced you.

One book per day for 20 days, in no particular order.

No explanations, no reviews, just covers.

Day 5

#booksky
💙📚
#books
#bookchallenge
November 23, 2024 at 10:52 PM
Reposted
Choose 20 books that have stayed with you or influenced you.

One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

Day 7

#booksky
💙📚
#books
#bookchallenge
November 26, 2024 at 12:29 AM
Reposted
Remember new users are coming on daily, unsure of engagement. The more posts you like and reply to, the strong the platform becomes !
November 25, 2024 at 7:05 PM
Reposted
Our first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out!
@vivianlilab.bsky.social @kingscollegelondon.bsky.social

www.cell.com/cell-reports...
IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells
The crosstalk between immune and epithelial cells is vital to maintain intestinal homeostasis. Lebrusant-Fernandez et al. identify NKT cells in the small intestine as key regulators of epithelial biol...
www.cell.com
November 24, 2024 at 11:00 AM
Reposted
Fomos de Gaia a Almendra, de um lado ao outro de Portugal. Na N222, há a “melhor estrada do mundo” e nas suas bermas há vários mundos. Reconhecida pela sua beleza, nós fomos conhecer quem a vive.
Pela Estrada Nacional 222, Portugal de um lado ao outro: as vidas além da paisagem
Fomos de Gaia a Almendra, de um lado ao outro de Portugal. Na N222, há a “melhor estrada do mundo” e nas suas bermas há vários mundos. Reconhecida pela sua beleza, nós fomos conhecer quem a vive.
www.publico.pt
November 23, 2024 at 2:01 PM
Reposted
It seems like things are picking up towards the end of the year 🏁🏎️

The VIVID-1 trial,mirikizumab in mod-severe #CD

Unlike SEQUENCE this is a double-blind, double-dummy, placebo-controlled AND active-control with ustekinumab AND not all patients had failed TNF

www.sciencedirect.com/science/arti...
November 22, 2024 at 6:19 AM