Jannat Ijaz
@jijaz.bsky.social
Scientist in Altos Labs (aging) | Post doc in Reik lab (lineage tracing and development) | PhD in Campbell Lab (chromothripsis/structural variation in cancer)
Reposted by Jannat Ijaz
Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in
@nature.com! We outline the scope, vision, opportunities and challenges of these projects here:
www.nature.com/articles/s41...
The human and non-human primate developmental GTEx projects - Nature
The developmental Genotype-Tissue Expression (dGTEx) projects will catalogue and integrate gene expression, regulation and genetics data across 120 human donors from birth to adulthood with developmen...
www.nature.com
January 15, 2025 at 4:40 PM
Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in
@nature.com! We outline the scope, vision, opportunities and challenges of these projects here:
www.nature.com/articles/s41...
Reposted by Jannat Ijaz
Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years!
"Prolonged persistence of mutagenic DNA lesions in somatic cells"
www.nature.com/articles/s41...
"Prolonged persistence of mutagenic DNA lesions in somatic cells"
www.nature.com/articles/s41...
Prolonged persistence of mutagenic DNA lesions in somatic cells - Nature
Persistent DNA lesions can occur throughout the human lifespan and can remain in the genome of affected cells for several years and generate a substantial proportion of the mutational burden.
www.nature.com
January 15, 2025 at 5:21 PM
Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years!
"Prolonged persistence of mutagenic DNA lesions in somatic cells"
www.nature.com/articles/s41...
"Prolonged persistence of mutagenic DNA lesions in somatic cells"
www.nature.com/articles/s41...