Reprocessed ALys Amyloids from EMPIAR-11785 Fändrich Lab

Helical Reconstruction of Amyloids in cryoSPARC?
We present guidelines, limitations & future perspectives for processing amyloids in cryoSPARC @structurabio.bsky.social.
Great collaboration of the Kelly Lab and @landerlab.bsky.social #cryoEM #amyloid www.biorxiv.org/content/10.1...

I often go back to this striking study: doi.org/10.1126/scie...

Check out our new preprint from the @landerlab.bsky.social, Stagg-Lab and Cianfrocco-Lab: CryoSift - An accessible and automated CNN-driven tool for cryo-EM 2D class selection www.biorxiv.org/content/10.1...
Happy testing: cryosift.org #cryoEM #CNN

Exited to share my first PostDoc contribution! Like Magellan explored the globe, you can explore your cryoEM data with Magellon. Congrats to all involved. Scott Stagg Lab & Michael Cianfrocco Lab @landerlab.bsky.social www.biorxiv.org/content/10.1... 🌎❄️🔬

Do you want to visualize motion in protein structures? I've used @chimerax.ucsf.edu and little python code to do just that github.com/schaefer-jh/.... Here is some ABC transporter magic. #LLM assisted #coding

New preprint. Mechanistic Plasticity of the RabGEFs Mon1-Ccz1 and Fuzzy-Inturned. Showing how TLD-RabGEFs adapt to different cellular functions. Congrats to first author @stephanwilmes.bsky.social from the Kümmel Lab. #cryoEM #openscience @arnemoeller.bsky.social doi.org/10.1101/2025...

Spot the dolphin.

Thrilled to see another chapter of my PhD at Universität Osnabrück published at Nature Structural & Molecular Biology! Read more about how to make Ceramides and the Ping-Pong-Mechanism here - rdcu.be/dZZUF Thanks to all from the groups of Arne Moeller and Florian Fröhlich! #cryoEM 🔬❄️

Happy to have contributed to solving Gaucher's disease GCase-LIMP-2 complex. Congrats to first Jan Philipp Dobert from Zunke-lab & Arnold-lab and all others. @MoellerGroup @Molecular_Neuro#b3d #cryoEM

researchsquare.com/article/rs-433…

Preprint Alert! 📣We've solved the first structure of a Ceramide Synthase.
Great Team work @FlorianFrhlich3 @MoellerGroup @DJanuliene @UniOsnabrueck
Thanks to co-first Lena Clausmeyer & Carolin Körner! #uos #cryoEM #openscience

doi.org/10.1101/2023.1…

Our paper on "Structure of the ceramide-bound SPOTS complex" is now out in @NatureComms - Fantastic teamwork with co-first Carolin Körner from @FlorianFrhlich3@MoellerGroup #CryoEM #UOS 🔬❄️

nature.com/articles/s4146…

Happy to have contributed to our latest paper with @UngermannLab @LarsLangemeyer @MoellerGroup spearheaded by Twitterless Sophie Grziwa.
Yck3 regulates membrane trafficking by phosphorylating I-BAR protein Ivy1.

doi.org/10.1242/jcs.26…

There is quiet nothing like sharing a new structure! "Structure of the metazoan Rab7 GEF complex Mon1-Ccz1-Bulli" form @MoellerGroup now out in PNAS.
Fantastic collaboration with co-first @stEricHerrmann and @StephanWilmes from @KuemmelLab and @UngermannLab. #cryoEM #UOS #b3d

Thrilled to share our new @biorxivpreprint: "Structure of the ceramide-bound SPOTS complex"
from @MoellerGroup @DJanuliene @krparey. Great collaboration with @FlorianFrhlich3 lab, spearheaded by Carolin Körner. #CryoEM

biorxiv.org/content/10.110…