Jerzy Szablowski
@jerzyszablowski.bsky.social
Assistant Professor at Rice Univ. Bioengineering. Developing molecular tools to interact with the brain and treat brain disorders.
Co-founder at Imprint Bio. Inc. NIH New Innovator, Packard Fellow, and DARPA YFA awardee.
www.szablowskilab.org
Co-founder at Imprint Bio. Inc. NIH New Innovator, Packard Fellow, and DARPA YFA awardee.
www.szablowskilab.org
How can you know if gene delivery in a primate worked Typically through expensive scans or histology. With
@vincentcostaphd.bsky.social
and co-authors we made synthetic markers that monitor gene delivery and Cre-dependent expression with a blood test:
www.biorxiv.org/content/10.1...
@vincentcostaphd.bsky.social
and co-authors we made synthetic markers that monitor gene delivery and Cre-dependent expression with a blood test:
www.biorxiv.org/content/10.1...
June 2, 2025 at 11:45 PM
How can you know if gene delivery in a primate worked Typically through expensive scans or histology. With
@vincentcostaphd.bsky.social
and co-authors we made synthetic markers that monitor gene delivery and Cre-dependent expression with a blood test:
www.biorxiv.org/content/10.1...
@vincentcostaphd.bsky.social
and co-authors we made synthetic markers that monitor gene delivery and Cre-dependent expression with a blood test:
www.biorxiv.org/content/10.1...
What is the next frontier in brain therapy? Small molecules act everywhere; our work targets brain regions with mm precision. Next frontier? Targeting microscale - neuronal connections, ensembles. Here, we test AAV9.retro for noninvasive transduction of neuronal projections. preprint comments
April 26, 2025 at 8:53 PM
What is the next frontier in brain therapy? Small molecules act everywhere; our work targets brain regions with mm precision. Next frontier? Targeting microscale - neuronal connections, ensembles. Here, we test AAV9.retro for noninvasive transduction of neuronal projections. preprint comments
We are starting our
@ARIA_research
Precision Neurotechnologies project and have two non-postdoc positions in neuroscience and bioengineering. This funding is independent of US government.
Jobs:
emdz.fa.us2.oraclecloud.com/hcmUI/Candid...
More info:
tinyurl.com/hwsnrwpe
-- please RT --
@ARIA_research
Precision Neurotechnologies project and have two non-postdoc positions in neuroscience and bioengineering. This funding is independent of US government.
Jobs:
emdz.fa.us2.oraclecloud.com/hcmUI/Candid...
More info:
tinyurl.com/hwsnrwpe
-- please RT --
February 17, 2025 at 11:26 PM
We are starting our
@ARIA_research
Precision Neurotechnologies project and have two non-postdoc positions in neuroscience and bioengineering. This funding is independent of US government.
Jobs:
emdz.fa.us2.oraclecloud.com/hcmUI/Candid...
More info:
tinyurl.com/hwsnrwpe
-- please RT --
@ARIA_research
Precision Neurotechnologies project and have two non-postdoc positions in neuroscience and bioengineering. This funding is independent of US government.
Jobs:
emdz.fa.us2.oraclecloud.com/hcmUI/Candid...
More info:
tinyurl.com/hwsnrwpe
-- please RT --
Did you all start sciencing harder recently, or something?
February 6, 2025 at 6:35 PM
Did you all start sciencing harder recently, or something?
qPCR can measure expression of virtually any gene... in homogenized tissues. Here, we show an "in-vivo qPCR" equivalent, where we measure a sequence-specific transcript with synthetic serum markers and enzyme-based signal amplification.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 12, 2024 at 4:51 PM
qPCR can measure expression of virtually any gene... in homogenized tissues. Here, we show an "in-vivo qPCR" equivalent, where we measure a sequence-specific transcript with synthetic serum markers and enzyme-based signal amplification.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...