Jeff Lee
@jeffylee.bsky.social
RNA Biologist | University of Glasgow
Reposted by Jeff Lee
🚨🚨 News from the @castello-lab.bsky.social and @shabazlab.bsky.social. Our work, led by Louisa Iselin, reveals pervasive changes in the RNA-bound proteome induced by interferon. #RNA, #immunity, #interferon, #host-virus www.biorxiv.org/content/10.1...
June 3, 2025 at 10:01 PM
🚨🚨 News from the @castello-lab.bsky.social and @shabazlab.bsky.social. Our work, led by Louisa Iselin, reveals pervasive changes in the RNA-bound proteome induced by interferon. #RNA, #immunity, #interferon, #host-virus www.biorxiv.org/content/10.1...
Reposted by Jeff Lee
Excited to share our latest work! We asked if and how TDP-43 regulates RNA transport in neurons and if this is misregulated in ALS. We found that it works to keep RNAs *out* of neurites, and that loss of TDP-43 activity results in specific RNAs aberrantly accumulating there.
March 3, 2025 at 3:55 PM
Excited to share our latest work! We asked if and how TDP-43 regulates RNA transport in neurons and if this is misregulated in ALS. We found that it works to keep RNAs *out* of neurites, and that loss of TDP-43 activity results in specific RNAs aberrantly accumulating there.
Reposted by Jeff Lee
Amazing work of our dear friends @ilandavis.bsky.social and @jeffylee.bsky.social characterising the interlinked roles of two key RBPs in drosophila brain development, congratulations 🍾🥂🎉🎉🎉 www.science.org/doi/10.1126/...
Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development
RNA binding protein combinations control neuronal identity through a network of temporal regulators.
www.science.org
February 17, 2025 at 7:02 PM
Amazing work of our dear friends @ilandavis.bsky.social and @jeffylee.bsky.social characterising the interlinked roles of two key RBPs in drosophila brain development, congratulations 🍾🥂🎉🎉🎉 www.science.org/doi/10.1126/...
Reposted by Jeff Lee
Jeff Lee et al paper from my lab is out now
www.science.org/doi/10.1126/...
I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.
www.science.org/doi/10.1126/...
I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.
Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development
RNA binding protein combinations control neuronal identity through a network of temporal regulators.
www.science.org
February 12, 2025 at 11:19 PM
Jeff Lee et al paper from my lab is out now
www.science.org/doi/10.1126/...
I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.
www.science.org/doi/10.1126/...
I am very grateful to Jeff, Nile's and Tamsin for all the hard work on this tour de force paper.
Jeff deserves more credit than me for masterminding it and the outstanding data analysis: 2 RBPs over 3 developmental times.
Following our recent publication, here’s a striking collage of developing fly brain! 🧠✨ Highlighting the dynamic expression of RNA-binding proteins Imp (green) and Syp (magenta) www.science.org/doi/10.1126/...
February 10, 2025 at 5:42 PM
Following our recent publication, here’s a striking collage of developing fly brain! 🧠✨ Highlighting the dynamic expression of RNA-binding proteins Imp (green) and Syp (magenta) www.science.org/doi/10.1126/...
🧠🔬How do RNA-binding proteins shape brain development? Our latest study reveals how Imp & Syp form combinatorial networks to regulate Drosophila neurogenesis. Excited to share this work in #ScienceAdvances!
📜 Read more: www.science.org/doi/10.1126/... #ilandavislab #RNA #neurogenesis
📜 Read more: www.science.org/doi/10.1126/... #ilandavislab #RNA #neurogenesis
Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development
RNA binding protein combinations control neuronal identity through a network of temporal regulators.
www.science.org
February 10, 2025 at 5:30 PM
🧠🔬How do RNA-binding proteins shape brain development? Our latest study reveals how Imp & Syp form combinatorial networks to regulate Drosophila neurogenesis. Excited to share this work in #ScienceAdvances!
📜 Read more: www.science.org/doi/10.1126/... #ilandavislab #RNA #neurogenesis
📜 Read more: www.science.org/doi/10.1126/... #ilandavislab #RNA #neurogenesis