Jean de Lima
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jeandelima.bsky.social
Jean de Lima
@jeandelima.bsky.social
Master’s degree in Immunology at @ImmunologyLIT | PhD candidate at @Immunologyking.bsky.social | Also casual guitar player and stove enthusiast 🔬🎸 👨‍🍳🇧🇷🇨🇭
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Excited to share our new preprint on Hif1a in lung CD4 T cells ⏲️🥧 It’s been a challenging but rewarding journey. Huge thanks to Carolyn for her brilliant mentorship and to all our collaborators for their support!
We've worked on Hif deletion in CD4 #Tcells for an embarrassingly long time. We gave up and had to rederive the T conditional KO mice after we stumbled on a phenotype in # NK cells from these mice (1+ years after data acquisition)

It's been long, slow and fascinating. In a nutshell...
HIF-1α+ CD4 T cells coordinate a tissue resident immune cell network in the lung https://www.biorxiv.org/content/10.1101/2025.06.13.659476v1
Excited to share our new preprint on Hif1a in lung CD4 T cells ⏲️🥧 It’s been a challenging but rewarding journey. Huge thanks to Carolyn for her brilliant mentorship and to all our collaborators for their support!
We've worked on Hif deletion in CD4 #Tcells for an embarrassingly long time. We gave up and had to rederive the T conditional KO mice after we stumbled on a phenotype in # NK cells from these mice (1+ years after data acquisition)

It's been long, slow and fascinating. In a nutshell...
HIF-1α+ CD4 T cells coordinate a tissue resident immune cell network in the lung https://www.biorxiv.org/content/10.1101/2025.06.13.659476v1
June 18, 2025 at 7:04 AM
Reposted by Jean de Lima
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues.

📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025

Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social

#EMBOBarrierTissues
Adaptive immunity in barrier tissues
Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…
meetings.embo.org
April 30, 2025 at 3:04 PM
Time course of the classic CCL19, CCL21, AND the more recent role of Ch25h in lymphocyte dynamics. Particularly intriguing to see Ch25h’s influence beyond mucosal sites. Fascinating work!
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
Sustained lymphocyte migration from blood into lymph nodes (LNs) is important for immune responses. The CC-chemokine receptor-7 (CCR7) ligand CCL21 is…
www.sciencedirect.com
December 23, 2024 at 5:07 PM
Excited for an amazing meeting in Basel, CH ❤️‍🔥 So much to learn, share, and enjoy!
Registration is live!! May 30th deadline for #EMBOTissueImmunity in Basel🇨🇭 (home to Eurocup 2025, Eurovision 2025, Art Basel, world renowned architecture and muuuuuch more!) Be our guest for groundbreaking #immunology discussion, swimming & fun along the Rhine.
meetings.embo.org/event/25-bar...
December 20, 2024 at 12:48 PM