Jacopo Pasqualini
@jcppsqln.bsky.social
> Mining microbial communities, terabase after terabase
> Theoretical Physicist turned Computational Biologist
> Postdoc at Torsten Schwede Lab in Basel
> 物の哀れ
> Theoretical Physicist turned Computational Biologist
> Postdoc at Torsten Schwede Lab in Basel
> 物の哀れ
Reposted by Jacopo Pasqualini
Fresh from bioRxiv our latest work introducing The Embedded Alphabet (TEA), a powerful new representation for protein sequences obtained by discretising ESM2 embeddings into 20 characters.
Pre-print: www.biorxiv.org/content/10.1...
🧵👇(1/n)
Pre-print: www.biorxiv.org/content/10.1...
🧵👇(1/n)
Rewriting protein alphabets with language models
Detecting remote homology with speed and sensitivity is crucial for tasks like function annotation and structure prediction. We introduce a novel approach using contrastive learning to convert protein...
www.biorxiv.org
December 1, 2025 at 10:28 AM
Fresh from bioRxiv our latest work introducing The Embedded Alphabet (TEA), a powerful new representation for protein sequences obtained by discretising ESM2 embeddings into 20 characters.
Pre-print: www.biorxiv.org/content/10.1...
🧵👇(1/n)
Pre-print: www.biorxiv.org/content/10.1...
🧵👇(1/n)
Reposted by Jacopo Pasqualini
Introducing CAMEO Structures & Complexes - automated weekly blind benchmarking of structure prediction servers. Now with heteromeric and protein-ligand complexes.
Join us and register your server now!
cameo3d.org
Join us and register your server now!
cameo3d.org
April 28, 2025 at 7:56 AM
Introducing CAMEO Structures & Complexes - automated weekly blind benchmarking of structure prediction servers. Now with heteromeric and protein-ligand complexes.
Join us and register your server now!
cameo3d.org
Join us and register your server now!
cameo3d.org
Reposted by Jacopo Pasqualini
🧪🧬🔬 Postdoc in Computational Structural Biology at the @biozentrum.unibas.ch & @sib.swiss in Basel, Switzerland.
www.biozentrum.unibas.ch/open-positio...
The position is initially funded for 3 years, possibility to start immediately.
#StructurePrediction, #Bioinformatics, #Uniprot3D, #AI
www.biozentrum.unibas.ch/open-positio...
The position is initially funded for 3 years, possibility to start immediately.
#StructurePrediction, #Bioinformatics, #Uniprot3D, #AI
February 26, 2025 at 11:01 AM
🧪🧬🔬 Postdoc in Computational Structural Biology at the @biozentrum.unibas.ch & @sib.swiss in Basel, Switzerland.
www.biozentrum.unibas.ch/open-positio...
The position is initially funded for 3 years, possibility to start immediately.
#StructurePrediction, #Bioinformatics, #Uniprot3D, #AI
www.biozentrum.unibas.ch/open-positio...
The position is initially funded for 3 years, possibility to start immediately.
#StructurePrediction, #Bioinformatics, #Uniprot3D, #AI
Reposted by Jacopo Pasqualini
Some very cool stuff from the group now in paper form:
“ModelArchive: a deposition database for computational macromolecular structural models”
doi.org/10.1016/j.jm...
And
“Comparing macromolecular complexes - a fully automated benchmarking suite” doi.org/10.21203/rs.... (under review)
“ModelArchive: a deposition database for computational macromolecular structural models”
doi.org/10.1016/j.jm...
And
“Comparing macromolecular complexes - a fully automated benchmarking suite” doi.org/10.21203/rs.... (under review)
Redirecting
doi.org
February 21, 2025 at 5:13 PM
Some very cool stuff from the group now in paper form:
“ModelArchive: a deposition database for computational macromolecular structural models”
doi.org/10.1016/j.jm...
And
“Comparing macromolecular complexes - a fully automated benchmarking suite” doi.org/10.21203/rs.... (under review)
“ModelArchive: a deposition database for computational macromolecular structural models”
doi.org/10.1016/j.jm...
And
“Comparing macromolecular complexes - a fully automated benchmarking suite” doi.org/10.21203/rs.... (under review)