Junsik Choi
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Junsik Choi
@jc2842.bsky.social
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Plant Bio Postdoc @ Whitehead
Epigenetics, genomics, nuclear lamina
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Reposted by Junsik Choi
dnarnaresearch.bsky.social
Nature’s pharmacy unlocked: a gene cluster conserved in nightshade plants powers withanolide biosynthesis. Engineered yeast + tobacco host the path forward

🌱 doi.org/10.1038/s414...
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis - Nature Communications
Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown. Here, the authors report the g...
doi.org
October 19, 2025 at 11:42 AM
Reposted by Junsik Choi
plantgenomics.bsky.social
Nascent CUT&Tag captures transcription factor binding after chromatin duplication
doi.org/10.1101/2025...

Automatic identification and annotation of MYB gene family members in plants
doi.org/10.1101/2021...
Nascent CUT&Tag captures transcription factor binding after chromatin duplication
DNA replication strips off all chromatin proteins, which must be reassembled behind the replication fork. To track chromatin reassembly on newly synthesized DNA, we developed Nascent CUT&Tag, a chroma...
doi.org
October 16, 2025 at 4:56 AM
Reposted by Junsik Choi
plantcellphysiol.bsky.social
The same but different... ♊

Wu et al. have performed comparative genomics analyses in legumes & other species to reveal the similarities & unique features of gene regulatory networks operating in nitrogen-fixing & arbuscular mycorrhizal symbioses

🔗 doi.org/10.1093/pcp/...

#PlantScience
Figure 1 (split into panels a-g) of the paper by Wu et al. showing Transcriptomic change in arbusculated and nodulated roots across different species. (a) bar chart showing DEGs in arbusculated roots of six plant species. (b) bar chart showing DEGs in nodulated roots of three legume species. (c) GO enrichment analysis showing words/phrases related to DEGs in arbusculated roots across six plant species. (d−f) Venn diagrams illustrating shared and unique DEGs between arbusculated and nodulated roots in three legume species. (g) 3 scatter plots comparing gene expression changes between AMS and NFS in M. trunculata, G. max and L. japonicus.
October 9, 2025 at 10:19 AM
Reposted by Junsik Choi
rensingstefan.bsky.social
Very happy and proud to share the #Spirogyra genome: 50 Mbp small, lacking almost all plastid division proteins and many transcription factors. Kudos to all the many people involved in this multi year project!
@jandevries.bsky.social
@watertoland.bsky.social
www.biorxiv.org/content/10.1...
October 11, 2025 at 9:20 AM
Reposted by Junsik Choi
plantgenomics.bsky.social
Uncertainty in joint Ancestral State Reconstruction: Improving accuracy and biological interpretability of ancestral state prediction
doi.org/10.1101/2025...
Uncertainty in joint Ancestral State Reconstruction: Improving accuracy and biological interpretability of ancestral state prediction
Ancestral state reconstruction (ASR) is a foundational tool in comparative biology, offering insights into the evolutionary history of lineages. With each new evolutionary model, our ability to estima...
doi.org
October 11, 2025 at 6:36 AM