Jay Roshe
jayroshe.bsky.social
Jay Roshe
@jayroshe.bsky.social
Interested in treating/preventing age-related ill health (dementia, cardiovascular disease, cancer, frailty, etc.) by targeting aspects of the biology of aging. Learn more: https://www.c-span.org/video/?511443-1/ageless
Reposted by Jay Roshe
This is a new and invaluable resource for international students in the US, or anyone thinking of studying in the US

The International Student Resource Center

It has a wealth of information about how to navigate all of the procedures and barriers, plus up-to-date information on shifting policy
International Student Resource Center
internationalstudent.us
November 5, 2025 at 10:48 PM
Reposted by Jay Roshe
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
October 7, 2025 at 5:49 PM
Reposted by Jay Roshe
See Hannah Ritchie's post to view the table of contents on the 50 questions she answers in her book:
www.sustainabilitybynumbers.com/p/clearing-t...
September 18, 2025 at 11:30 AM
See Hannah Ritchie's post to view the table of contents on the 50 questions she answers in her book:
www.sustainabilitybynumbers.com/p/clearing-t...
September 18, 2025 at 11:30 AM
A nationwide Danish study suggests infections with human papillomavirus (HPV) types 16 and 18 have been virtually eliminated since vaccination began in 2008:
www.eurosurveillance.org/content/10.2...
Human papillomavirus prevalence in first, second and third cervical cell samples from women HPV-vaccinated as girls, Denmark, 2017 to 2024: data from the Trial23 cohort study
BACKGROUND Danish women vaccinated with the 4-valent human papillomavirus (HPV) vaccine (HPV types: 6/11/16/18) at age 14 in 2008 reached screening age in 2017, allowing assessment of long-term effects on prevalence, persistence and incidence of HPV infections. AIM To examine the HPV status of cervical samples over time among women vaccinated as girls. METHODS Between February 2017 and February 2024, residual material from cytology-analysed samples collected through the ‘Trial23’ study, part of the national screening programme, was tested for HPV16/18 and non-vaccine high-risk (HR) HPV types. Prevalence in first, second and third samples, and persistence and incidence between samples were calculated. RESULTS Over 7 years, 8,659 women provided at least one sample, 5,835 at least two and 2,461 at least three. In 7,800 vaccinated women, HPV16/18 prevalence was 0.4% (95% confidence interval (CI): 0.2–0.5), 0.3% (95% CI: 0.1–0.4) and 0.2% (95% CI: 0.0–0.4) in three consecutive samples. Prevalence of non-vaccine HR HPV was 32% (95% CI: 31–33), 28% (95% CI: 27–29) and 31% (95% CI: 29–33). Persistence of HPV16/18 and non-vaccine HPV among vaccinated women was 40% and 53%. In adjusted analyses comparing vaccinated vs unvaccinated women, incidence was significantly lower for HPV16/18 (adjusted relative risk (aRR) < 0.10) while incidence of non-vaccine HR HPV types was higher (aRR: 1.66; 95% CI: 1.12–2.45). No significant difference was observed for persistence. CONCLUSION Our study provides real-world evidence of stable protection against HPV16/18 infections in women vaccinated as girls. Less intensive screening seems reasonable until women vaccinated with the 9-valent vaccine reach screening age, when screening should be reconsidered.
www.eurosurveillance.org
September 11, 2025 at 8:32 AM
Reposted by Jay Roshe
PhD candidate Jillian Cox in the Ocañas Lab at University of Oklahoma spoke on the A4LI Scientist Spotlight about her research into brain aging and the different influences of sex chromosomes in brain diseases and disorders:
open.spotify.com/episode/1HVe...
Episode 25 - Jillian Cox
A4LI Scientist Spotlight · Episode
open.spotify.com
August 19, 2025 at 7:10 PM
PhD candidate Jillian Cox in the Ocañas Lab at University of Oklahoma spoke on the A4LI Scientist Spotlight about her research into brain aging and the different influences of sex chromosomes in brain diseases and disorders:
open.spotify.com/episode/1HVe...
Episode 25 - Jillian Cox
A4LI Scientist Spotlight · Episode
open.spotify.com
August 19, 2025 at 7:10 PM
Several people nearly died after receiving peptide injections at RAADfest, known for including fringe quacks. There's a great deal of legitimate medical research on aging biology; there are also dangerous, irresponsible people who damage the field's credibility. www.propublica.org/article/pept...
A Las Vegas Festival Promised Ways to Cheat Death. Two Attendees Left Fighting for Their Lives.
Authorities are investigating why two women fell ill at the Revolution Against Aging and Death Festival. They both received peptide injections, an alternative therapy promoted by Robert F. Kennedy Jr....
www.propublica.org
August 10, 2025 at 8:07 PM
Age1, founded by Laura Deming and Alex Colville, created a scorecard of 11 major pharma companies on their involvement in medical research targeting aspects of the biology of aging. Eli Lilly, Novartis, and Novo Nordisk were the top three:
www.librariesforthefuture.bio/p/age1s-2025...
age1’s 2025 1st Annual Pharma Aging Report Card
Grading the giants on their race to extend human healthspan
www.librariesforthefuture.bio
August 2, 2025 at 1:03 PM
Reposted by Jay Roshe
A return to independence. Current treatments for severe brain damage only restore partial function. FRONT aims to heal and repair brain tissue and enable individuals with brain damage to recover lost functions.

Register for FRONT Proposers' Day on August 8 (by August 5): arpa-h.gov/explore-fund...
July 22, 2025 at 2:14 PM
The German National Academy of Sciences published a short paper in which they advocate for basic and clinical research targeting the biology of aging to ameliorate age-related illness. Link to English translation:

www.leopoldina.org/fileadmin/re...
www.leopoldina.org
July 27, 2025 at 4:21 PM
Reposted by Jay Roshe
Seth Ashby,  a research associate in University of Maine's Angeli Lab, chatted with A4LI Scientist Spotlight. Topics include Seth's experience working at a short-staffed nursing home during the pandemic, his interest in aging research, growing up in Maine, and more: open.spotify.com/episode/3S78...
Episode 24 - Seth Ashby
A4LI Scientist Spotlight · Episode
open.spotify.com
July 16, 2025 at 9:52 PM
Seth Ashby,  a research associate in University of Maine's Angeli Lab, chatted with A4LI Scientist Spotlight. Topics include Seth's experience working at a short-staffed nursing home during the pandemic, his interest in aging research, growing up in Maine, and more: open.spotify.com/episode/3S78...
Episode 24 - Seth Ashby
A4LI Scientist Spotlight · Episode
open.spotify.com
July 16, 2025 at 9:52 PM
Reposted by Jay Roshe
Anyone interested in a deep dive of Jean Hebert's FRONT program at ARPA-H can download the ISO at this page (scroll down to the PDF link): sam.gov/opp/89224bcb...
SAM.gov
sam.gov
July 10, 2025 at 9:53 PM
Reposted by Jay Roshe
Welcome news: "ARPA-H launches groundbreaking Functional Repair of Neocortical Tissue (FRONT) program, to restore brain function and return patients to independence". Many congratulations to Jean Hebert, FRONT’s Program Manager arpa-h.gov/news-and-eve...
ARPA-H launches program to restore brain function and return patients to independence
The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...
arpa-h.gov
July 10, 2025 at 6:18 PM
Informative post by Dr. Christin Glorioso on measurements of biological age and her work on the brain. She covers six criteria that "clocks" should offer to be useful and how three broad components of NeuroAge meet the challenge:

drglorioso.substack.com/p/what-is-bi...
June 29, 2025 at 1:41 PM
Reposted by Jay Roshe
Treating types of cancer with CAR T-cell therapy is expensive and inconvenient, but a streamlined approach that creates the therapy within the body could make the intervention cheaper and easier
CAR T-cell therapy could be made in the body of someone with cancer
Treating types of cancer with CAR T-cell therapy is expensive and inconvenient, but a streamlined approach that creates the therapy within the body could make the intervention cheaper and easier
www.newscientist.com
June 21, 2025 at 10:48 AM
Reposted by Jay Roshe
Andrew Brack gives details on his ARPA-H program PROSPR (Proactive Solutions for Prolonging Resilience), which aims to establish FDA-accepted aging biomarkers and run trials with repurposed and next-gen. interventions.

He gets into PROSPR and ARPA-H at 17:50 - open.spotify.com/episode/1aYy...
Episode 27 - Andrew Brack, PhD
A4LI H-SPAN Podcast · Episode
open.spotify.com
June 19, 2025 at 10:58 PM
Reposted by Jay Roshe
That’s why we’re calling on volunteers to join us at A4LI. Whether you’re new to advocacy or have years of experience, your voice matters. Grassroots momentum is what will carry this movement through uncertainty and toward lasting change.

👉 Sign up to volunteer at a4li.org/get-involved/ today!
June 18, 2025 at 6:52 PM
Andrew Brack gives details on his ARPA-H program PROSPR (Proactive Solutions for Prolonging Resilience), which aims to establish FDA-accepted aging biomarkers and run trials with repurposed and next-gen. interventions.

He gets into PROSPR and ARPA-H at 17:50 - open.spotify.com/episode/1aYy...
Episode 27 - Andrew Brack, PhD
A4LI H-SPAN Podcast · Episode
open.spotify.com
June 19, 2025 at 10:58 PM
Reposted by Jay Roshe
Attention trainees: 𝗡𝗼𝘄 𝗶𝘀 𝘁𝗵𝗲 𝘁𝗶𝗺𝗲 𝗳𝗼𝗿 𝗴𝗿𝗮𝘀𝘀𝗿𝗼𝗼𝘁𝘀 𝗮𝗰𝘁𝗶𝗼𝗻.

While headlines swirl with political turmoil and federal funding for biomedical research faces cuts, one truth remains: Americans are living longer, but not healthier.
June 18, 2025 at 6:50 PM
Reposted by Jay Roshe
Now, a team at Northeastern University has unraveled a key piece of this biological puzzle. In a study, the researchers reveal an elegant molecular mechanism that acts like a GPS coordinate system for regenerating cells.
Scientists Discover the Key to Axolotls’ Ability to Regenerate Limbs
A new study reveals the key lies not in the production of a regrowth molecule, but in that molecule's controlled destruction. The discovery could inspire future regenerative medicine.
www.wired.com
June 17, 2025 at 10:09 PM
Eli Lilly and BioAge recently stopped a Phase 2 clinical trial due to safety concerns, but Lilly has entered an agreement with Juvena in another attempt to preserve muscle mass during weight loss:
www.biospace.com/business/lil...
Lilly Bites Again in $650M Muscle-Preserving Treatment Pact With Juvena
The deal is Lilly’s second obesity tie-up in a week, after sinking up to $870 million into an agreement with Camurus to develop long-acting versions of molecules against GLP-1 and other incretins.
www.biospace.com
June 11, 2025 at 10:12 PM
Reposted by Jay Roshe
People in the Bay Area interested in data science, bioinformatics, machine learning, and aging biology may be interested in signing up for this 2-day hackathon to turn convoluted data into ready-to-use resources for researchers:

lu.ma/a2ag12ya
Longevity x AI Hackathon · Luma
About The Event From June 14-15, Seanome and Frontier Tower are hosting a 2-day hackathon bringing together longevity and AI for the global ML community. No…
lu.ma
June 7, 2025 at 1:50 PM
People in the Bay Area interested in data science, bioinformatics, machine learning, and aging biology may be interested in signing up for this 2-day hackathon to turn convoluted data into ready-to-use resources for researchers:

lu.ma/a2ag12ya
Longevity x AI Hackathon · Luma
About The Event From June 14-15, Seanome and Frontier Tower are hosting a 2-day hackathon bringing together longevity and AI for the global ML community. No…
lu.ma
June 7, 2025 at 1:50 PM