Janine Brunner
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janinebrunner.bsky.social
Janine Brunner
@janinebrunner.bsky.social
Group Leader VIB and Assistant Professor VUB Brussels, Belgium - Biochemist - Structural biologist - interested in #MembraneProteins #cryoEM - nature - paragliding
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.

Or from a single dish of HEK cell culture in the case of two membrane proteins.

Out in Nature Methods now! lnkd.in/gpyBSceg

Wonderful collaboration with the Efremov lab.
November 14, 2025 at 6:38 PM
Happy to announce our most recent preprint: Stereoselectivity and plasticity of a common binding pocket in TRPM3, by cryo-EM and elecrophysiology. Great collaboration with the Voets, Vriens and CISTIM labs.

www.biorxiv.org/content/10.1...
August 28, 2025 at 6:39 PM
Cryo-EM structures of mammalian membrane proteins from a single cell culture dish?

Yes, Micro ISOlation (MISO) sample preparation makes it possible.

www.biorxiv.org/content/10.1...

Happy to be part of this exciting story and wonderful collaboration with the Rouslan Efremov lab.
January 16, 2025 at 9:27 AM