Jane Tulloch
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janetulloch.bsky.social
Jane Tulloch
@janetulloch.bsky.social
Lab Manager for the Spires-Jones Lab, UK DRI, University of Edinburgh. Allotment newbie, fresh air obsessive, boy and dog Mum, absolutely loves to gallivant.
Reposted by Jane Tulloch
Our paper in Nature Comms is now online! Summary below but in short we use living human brain slice cultures in a number of different ways to model dementia processes. Big team effort led by myself, @robertmcgeachan.bsky.social and @clairedurrant1.bsky.social rdcu.be/ej647
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures
Nature Communications - Understanding synapse loss in Alzheimer’s disease has been hampered by a lack of human model systems. Here, the authors show that manipulation of physiological or...
rdcu.be
April 30, 2025 at 3:22 PM
Reposted by Jane Tulloch
Delighted to share our paper examining synaptic tau in PSP. Many thanks to @robertmcgeachan.bsky.social @clairedurrant1.bsky.social and our many collaborators and funders. And extra special thanks to tissue donors who make this work possible.
📢Fabulous new paper from @tspiresjones.bsky.social, @clairedurrant1.bsky.social & team describes new mechanisms in Progressive Supranuclear Palsy, suggesting that targeting tau in synapses is a promising approach for future treatments.

Full paper➡️www.nature.com/articles/s41593-025-01992-5 🧠
July 17, 2025 at 11:54 AM
Reposted by Jane Tulloch
Fantastic to see this work from @clairedurrant1.bsky.social group out in print! Important results using living human brain tissue to study Alzheimer’s disease www.nature.com/articles/s41...
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures - Nature Communications
Understanding synapse loss in Alzheimer’s disease has been hampered by a lack of human model systems. Here, the authors show that manipulation of physiological or pathological Aβ has differing effects...
www.nature.com
April 30, 2025 at 12:02 PM
Reposted by Jane Tulloch
Amazing to welcome HRH The Duchess of Edinburgh, Patron of Race Against Dementia to our lab! An incredible opportunity to showcase our work with living human brain slice cultures and the importance of investing in dementia research. We are very lucky to have her support.
April 1, 2025 at 8:18 AM
Reposted by Jane Tulloch
March 3, 2025 at 2:29 PM
Signing off for Christmas after a great December. Grateful for the good stuff.
December 23, 2024 at 6:06 PM
Reposted by Jane Tulloch
In case anyone on BlueSky hasn't seen it, this may be the funniest scientific study ever published. Bringing it up now as the amazing @scotsfriction.bsky.social has just issued a "teaspoon amnesty" for our common room www.bmj.com/content/331/...
November 28, 2024 at 11:18 AM
Reposted by Jane Tulloch
🧠 130 people now in this UK Dementia Starter Pack! 🧠
📈 (50 more than 2 days ago!) 📈

A great mix of Profs/PIs/Post-docs/PhDs/Technicians.

Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋
go.bsky.app/S6FfsTp
November 21, 2024 at 2:08 PM
Reposted by Jane Tulloch
Got the BEST email over the weekend about provisional paper acceptance and still smiling and doing paper accepted dance. So a heads up that in the not too distant future this amazing data will have a "forever" peer-reviewed home: www.medrxiv.org/content/10.1...
snoopy is dancing on a green background with the words happy dance below him
ALT: snoopy is dancing on a green background with the words happy dance below him
media.tenor.com
November 19, 2024 at 11:50 AM
Reposted by Jane Tulloch
Hi Blue Sky folks 😃
We bring together the diverse community of brain & mind researchers across the Uni of Edinburgh to promote interdisciplinary collaboration & positive research culture🧠
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November 15, 2024 at 3:48 PM