James Krieger
jameskrieger.bsky.social
James Krieger
@jameskrieger.bsky.social
Senior data scientist in computational structural biology, protein dynamics and cryoem | Marie Sklododowska-Curie fellow w Jose Maria Carazo and Carlos Oscar Sorzano | postdoc w Ivet Bahar
Our new paper in Nature provides a structural framework for GluA3, a disease-prone AMPA glutamate receptors - previously unseen interfaces offer sites for drug development: www.nature.com/articles/s41...
Architecture, dynamics and biogenesis of GluA3 AMPA glutamate receptors - Nature
Nature - Architecture, dynamics and biogenesis of GluA3 AMPA glutamate receptors
www.nature.com
July 2, 2025 at 6:29 AM
Reposted by James Krieger
(3) This paper is now out for review again (woo!); if you have read this and received it to review - please consider writing your review in light of our response to reviewers!
November 10, 2024 at 2:19 PM
Reposted by James Krieger
(2) Further, @fraserlab.bsky.social conducted a great public peer review of this (thanks Daphne, CJ, and Jamie)! We want to respond to their comments, as well as some replies to our original reviewers. This response-to-reviewers can be found here: www.dropbox.com/scl/fi/v5iqy...
November 10, 2024 at 2:19 PM
#HiSciSky

I’m a research fellow in computational biology. I use molecular dynamics simulations, normal mode analysis and cryoem to study protein dynamics. I develop methods and study particular proteins, especially AMPA ionotropic glutamate receptors (#neuroskyence) and SARS-CoV-2 spikes (covid)
October 2, 2023 at 2:37 PM