James Davies
@james-s-davies.bsky.social
Researcher interested in how molecules traverse membranes. Structural biology, biochemistry and biophysics. Views are my own.
Check out our new paper:
🔗 www.cell.com/structure/fu...
We explored how sulfate-reducing bacteria import isethionate, a sulfur-containing molecule found in the environment and produced by microbes in the human gut. We captured a structure of the IseQM TRAP transporter in a substrate-bound state.
🔗 www.cell.com/structure/fu...
We explored how sulfate-reducing bacteria import isethionate, a sulfur-containing molecule found in the environment and produced by microbes in the human gut. We captured a structure of the IseQM TRAP transporter in a substrate-bound state.
Structural basis of isethionate transport by a TRAP transporter from a sulfate-reducing bacterium
Newton-Vesty et al. used a megabody fiducial to determine the cryo-EM structure of
an isethionate TRAP transporter, revealing the substrate and Na+-binding sites. Transport
is dependent on Na+ and the...
www.cell.com
November 9, 2025 at 8:45 PM
Check out our new paper:
🔗 www.cell.com/structure/fu...
We explored how sulfate-reducing bacteria import isethionate, a sulfur-containing molecule found in the environment and produced by microbes in the human gut. We captured a structure of the IseQM TRAP transporter in a substrate-bound state.
🔗 www.cell.com/structure/fu...
We explored how sulfate-reducing bacteria import isethionate, a sulfur-containing molecule found in the environment and produced by microbes in the human gut. We captured a structure of the IseQM TRAP transporter in a substrate-bound state.
Reposted by James Davies
#microsky finally a TRAP transporter that is *not* the Neu5Ac-transporting SiaPQM ;-)
www.cell.com/structure/fu...
www.cell.com/structure/fu...
Structural basis of isethionate transport by a TRAP transporter from a sulfate-reducing bacterium
Newton-Vesty et al. used a megabody fiducial to determine the cryo-EM structure of
an isethionate TRAP transporter, revealing the substrate and Na+-binding sites. Transport
is dependent on Na+ and the...
www.cell.com
November 6, 2025 at 1:29 AM
#microsky finally a TRAP transporter that is *not* the Neu5Ac-transporting SiaPQM ;-)
www.cell.com/structure/fu...
www.cell.com/structure/fu...