Jalil Rasgado Toledo
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jalilrt.bsky.social
Jalil Rasgado Toledo
@jalilrt.bsky.social
PhD student in biomedical sciences @inbunam
Working lab: @LabGarza
Interest: #MRI #DataScience #MentalDisorders #SocialDynamics

Zapoteco de nacimiento
Reposted by Jalil Rasgado Toledo
New paper by @jalilrt.bsky.social , @egarza.bsky.social and friends. "The effect of chronic stress and chronic alcohol intake on behavior, brain volume, and functional connectivity in a longitudinal rat model". doi.org/10.1093/brai...
The effect of chronic stress and chronic alcohol intake on behavior, brain volume, and functional connectivity in a longitudinal rat model
Rasgado-Toledo, et al. reported sex-dependent and region-specific effects of combined ethanol exposure and chronic stress on both the rat brain volume and
doi.org
November 3, 2025 at 8:34 PM
Come to Querétaro!, we have tacos and science
Registrations are open for the 2nd International Symposium on Addiction Research (ISAR) 2025 in Querétaro, Mexico, from August 25-27. Come visit us and show your work! addictions.inb.unam.mx
May 14, 2025 at 11:52 PM
This pipeline saved my PhD
Germann et al. propose a new deformation-based morphometry pipeline to measure longitudinal within-subject volumetric changes: doi.org/10.52294/001...

@fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social
April 14, 2025 at 9:52 PM
Reposted by Jalil Rasgado Toledo
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
April 11, 2025 at 12:35 PM
Reposted by Jalil Rasgado Toledo
this happened today and this felt so good. Thanks @mallarchak.bsky.social and team!
March 13, 2025 at 3:19 PM
Reposted by Jalil Rasgado Toledo
New preprint by Cindy Lucero and Chloe Anastassiadis examining modifiable dementia risk factors (exercise and diet) in a mouse model of Alzheimer’s

www.biorxiv.org/content/10.1...
Examining Alzheimer's Disease Modifiable Risk Factors: Impact of Physical Activity and Diet on Neuroanatomy and Behaviour in Mice
Dementia, a global public health challenge, is significantly influenced by lifestyle factors such as obesity. This study examines the impact of obesity and intervention approaches -physical exercise, ...
www.biorxiv.org
March 2, 2025 at 8:28 PM
Reposted by Jalil Rasgado Toledo
New preprint from the lab: www.biorxiv.org/content/10.1...
This was led by former Bachelor student Débora Elizarrarás and postdoc César Carranza. Here we wanted to study structural brain changes in opiod self-administration. Specifically if there was a link between MRI volume and neuroinflamation.
Morphine self-administration induces region-specific brain volume changes and microglial phenotypic alterations without affecting neuronal density in male Wistar rats
Addiction to opioids, including morphine, is a major public health crisis in the U.S. It has been associated with brain volume changes in reward-related regions, neuronal death, and neuroinflammation....
www.biorxiv.org
February 26, 2025 at 7:53 PM
The project I have been working on for 4 years. I stressed myself in the same way I stressed my rats, but at least they didn't become alcoholics.

My advice of the day: it may seem like a good idea to consume alcohol when stressed, but it's not
New work let by PhD student at the lab
@jalilrt.bsky.social
.
Does chronic stress increases alcohol drinking in adolescent rats and how does that affect their behavior, brain structure and functional connectivity, and is there an effect of sex?

www.biorxiv.org/content/10.1...
www.biorxiv.org
February 15, 2025 at 8:54 PM
Reposted by Jalil Rasgado Toledo
Reposted by Jalil Rasgado Toledo
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky

1. The importance of stupidity in scientific research

Open Access
journals.biologists.com/jcs/article/...
November 24, 2024 at 1:54 PM
The entire team behind the amazing scientific research at the cerebral imaging centre. Thanks to @mallarchak.bsky.social for hosting me during these months, and to @egarza.bsky.social to make it possible. I can't summarize everything I learned and the wonderful people I met during my stay. Thanks!!
December 6, 2024 at 10:58 PM