Jakob Woerner
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jakobwoerner.bsky.social
Jakob Woerner
@jakobwoerner.bsky.social
Genomics and Computational Biology PhD student at UPenn 🧬
Likewise!
September 5, 2025 at 12:51 AM
Fair point, one is cheaper, one is generally more predictive. A key point of the work is to find where integrating genetic information might provide additional insight beyond what proteomics can show
July 16, 2025 at 2:44 PM
And interestingly, ProRS values in the disease population are elevated even a decade before diagnosis! These scores then continue to rise up until diagnosis.

It'll be interesting to see how proteomics will continue to grow to help identify disease states and its application for precision medicine
July 15, 2025 at 1:53 AM
While proteomic risk scores (ProRS) provide a dynamic look at a person's current health status, polygenic risk scores (PRS) can further stratify individuals by risk across a range of diseases
July 15, 2025 at 1:41 AM