@jaisondsa.bsky.social
Reposted
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
August 1, 2025 at 12:58 AM
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
Reposted
Pfs48/45 nanobodies block transmission
🦟 Pfs48/45 Nb-Fc reduce oocyst numbers
💎 Structure of transmission-blocking Nb with Pfs48/45
👐🏽 Bispecific Nb-Fc targeting both Pfs230 and Pfs48/45
🧑🏻🔬 PhD student Frankie Lyons 1st Author 🥳
Please repost and happy reading!
www.biorxiv.org/content/10.1...
🦟 Pfs48/45 Nb-Fc reduce oocyst numbers
💎 Structure of transmission-blocking Nb with Pfs48/45
👐🏽 Bispecific Nb-Fc targeting both Pfs230 and Pfs48/45
🧑🏻🔬 PhD student Frankie Lyons 1st Author 🥳
Please repost and happy reading!
www.biorxiv.org/content/10.1...
Pfs48/45 nanobodies block Plasmodium falciparum transmission
Malaria parasite fertilisation occurs within the Anopheles mosquito midgut. Interventions that inhibit parasite fertilisation prevent ongoing transmission and are important for malaria elimination eff...
www.biorxiv.org
April 26, 2025 at 11:58 PM
Pfs48/45 nanobodies block transmission
🦟 Pfs48/45 Nb-Fc reduce oocyst numbers
💎 Structure of transmission-blocking Nb with Pfs48/45
👐🏽 Bispecific Nb-Fc targeting both Pfs230 and Pfs48/45
🧑🏻🔬 PhD student Frankie Lyons 1st Author 🥳
Please repost and happy reading!
www.biorxiv.org/content/10.1...
🦟 Pfs48/45 Nb-Fc reduce oocyst numbers
💎 Structure of transmission-blocking Nb with Pfs48/45
👐🏽 Bispecific Nb-Fc targeting both Pfs230 and Pfs48/45
🧑🏻🔬 PhD student Frankie Lyons 1st Author 🥳
Please repost and happy reading!
www.biorxiv.org/content/10.1...
Reposted
Stabilized PvRBP2b variants - wonderful collab with Sarel Fleishman
🔥Increased yields and thermal stability
✌️Maintains human mAb recognition
🩸Sensitivity as a sero-diagnostic for P. vivax
💕 Editors Pick
👨🏻🔬First paper for PhD student Jaison
Please read & repost!
www.jbc.org/article/S002...
🔥Increased yields and thermal stability
✌️Maintains human mAb recognition
🩸Sensitivity as a sero-diagnostic for P. vivax
💕 Editors Pick
👨🏻🔬First paper for PhD student Jaison
Please read & repost!
www.jbc.org/article/S002...
Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax
Plasmodium vivax is emerging as the most prevalent species causing malaria outside
Africa. Most P. vivax infections are relapses due to the reactivation of the dormant
liver stage parasites (hypnozoit...
www.jbc.org
March 6, 2025 at 4:51 AM
Stabilized PvRBP2b variants - wonderful collab with Sarel Fleishman
🔥Increased yields and thermal stability
✌️Maintains human mAb recognition
🩸Sensitivity as a sero-diagnostic for P. vivax
💕 Editors Pick
👨🏻🔬First paper for PhD student Jaison
Please read & repost!
www.jbc.org/article/S002...
🔥Increased yields and thermal stability
✌️Maintains human mAb recognition
🩸Sensitivity as a sero-diagnostic for P. vivax
💕 Editors Pick
👨🏻🔬First paper for PhD student Jaison
Please read & repost!
www.jbc.org/article/S002...
Excited to share our latest work on stabilizing PvRBP2b, a key step toward P. vivax malaria diagnostics!
Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with @thamlab.bsky.social
www.jbc.org/article/S002...
Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with @thamlab.bsky.social
www.jbc.org/article/S002...
Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax
Plasmodium vivax is emerging as the most prevalent species causing malaria outside
Africa. Most P. vivax infections are relapses due to the reactivation of the dormant
liver stage parasites (hypnozoit...
www.jbc.org
March 6, 2025 at 10:49 AM
Excited to share our latest work on stabilizing PvRBP2b, a key step toward P. vivax malaria diagnostics!
Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with @thamlab.bsky.social
www.jbc.org/article/S002...
Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with @thamlab.bsky.social
www.jbc.org/article/S002...