Jahn Zhong
@jahnzhong.bsky.social
Reposted by Jahn Zhong
We created one of the largest antibody bottom-up proteomics datasets to query the impact of experimental and computational parameters on the reconstruction of antibody sequences. www.biorxiv.org/content/10.1... Brilliant work by @mchernigovskaya.bsky.social, Khang Le Quy and Igor Snapkow.
Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases
The circulating antibody repertoire is crucial for immune protection, holding significant immunological and biotechnological value. While bottom-up mass spectrometry (MS) is the most widely used prote...
www.biorxiv.org
November 18, 2024 at 6:14 PM
We created one of the largest antibody bottom-up proteomics datasets to query the impact of experimental and computational parameters on the reconstruction of antibody sequences. www.biorxiv.org/content/10.1... Brilliant work by @mchernigovskaya.bsky.social, Khang Le Quy and Igor Snapkow.
Reposted by Jahn Zhong
Someone got the covid vaccination 217 times (two hundred and seventeen, or appx one every five days) and "did not report any vaccination-related side effects" and "showed no abnormalities attributable to hypervaccination" 🧪🧬🧶
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual
Prime-boost vaccinations can enhance immune responses,1 whereas chronic antigen exposure
can cause immune tolerance.2 In humans, the benefits, limitations, and risks of repetitive
vaccination remain p...
www.thelancet.com
March 5, 2024 at 7:40 AM
Someone got the covid vaccination 217 times (two hundred and seventeen, or appx one every five days) and "did not report any vaccination-related side effects" and "showed no abnormalities attributable to hypervaccination" 🧪🧬🧶
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Jahn Zhong
Our work on antibody developability is out! We present a cartography of the developability landscapes of native and human-engineered antibodies. This study was a team effort of Habib Bashour, @evasmorodina.bsky.social, Matteo Pariset, and @jahnzhong.bsky.social from @victorgreiff.bsky.social, UiO
October 31, 2023 at 7:54 AM
Our work on antibody developability is out! We present a cartography of the developability landscapes of native and human-engineered antibodies. This study was a team effort of Habib Bashour, @evasmorodina.bsky.social, Matteo Pariset, and @jahnzhong.bsky.social from @victorgreiff.bsky.social, UiO