Jacqueline Ehrlich
@jacquelineehrlich.bsky.social
Cornell PhD Candidate in the Kawate Lab | #membraneprotein #cryoEM & #celegans devotee | midwesterner 🌽 do-er 🏋️♀️be-er🧘♀️auntie 🤱
Loyal forever true ❤️💛 big thanks to career services at ISU CALS for the feature! career.cals.iastate.edu/news/2025/yo...
Young Alum of the Month: Jacqueline Ehrlich
career.cals.iastate.edu
November 13, 2025 at 4:23 PM
Loyal forever true ❤️💛 big thanks to career services at ISU CALS for the feature! career.cals.iastate.edu/news/2025/yo...
Happy Halloween from the Kawate lab! Lanes of my *oriole* gel from left to right: ladder, Pannexin 1, MSP2N2, and reconstituted Pannexin1 in MSP2N2 nanodiscs 🤓
October 31, 2025 at 3:42 PM
Happy Halloween from the Kawate lab! Lanes of my *oriole* gel from left to right: ladder, Pannexin 1, MSP2N2, and reconstituted Pannexin1 in MSP2N2 nanodiscs 🤓
Reposted by Jacqueline Ehrlich
Two new papers from our lab 😀!
Seipin beyond LDs: balances ER sphingolipids & glycerolipids, key for protein secretion (incl. Cav1). www.cell.com/cell-reports...
ER→LD traffic: lateral steric repulsion shapes how monotopic ER proteins partition onto LDs. www.science.org/doi/10.1126/...
Seipin beyond LDs: balances ER sphingolipids & glycerolipids, key for protein secretion (incl. Cav1). www.cell.com/cell-reports...
ER→LD traffic: lateral steric repulsion shapes how monotopic ER proteins partition onto LDs. www.science.org/doi/10.1126/...
Steric repulsion counteracts ER–to–lipid droplet protein movement
Steric hindrance affects the relocation of ER-to-LD proteins and primarily regulates the LD proteome.
www.science.org
September 28, 2025 at 11:57 AM
Two new papers from our lab 😀!
Seipin beyond LDs: balances ER sphingolipids & glycerolipids, key for protein secretion (incl. Cav1). www.cell.com/cell-reports...
ER→LD traffic: lateral steric repulsion shapes how monotopic ER proteins partition onto LDs. www.science.org/doi/10.1126/...
Seipin beyond LDs: balances ER sphingolipids & glycerolipids, key for protein secretion (incl. Cav1). www.cell.com/cell-reports...
ER→LD traffic: lateral steric repulsion shapes how monotopic ER proteins partition onto LDs. www.science.org/doi/10.1126/...
Reposted by Jacqueline Ehrlich
Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way! #lipidtime #compchem
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Molecular basis for the regulation of membrane proteins through preferential lipid solvation - Nature Chemical Biology
Static protein structures can capture the association of lipids, but it is unclear whether the association is due to lipids acting as long-lived ligands or the solvation of preferred lipids around the protein. A computational-experimental framework has now shown that for the protein CLC-ec1, it is the change in lipid solvation energies that drives dimerization, with preferred lipids around the protein modulating this driving force.
www.nature.com
September 26, 2025 at 3:29 PM
Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way! #lipidtime #compchem
www.nature.com/articles/s41...
www.nature.com/articles/s41...
POV: you venture over to the #celegans side of the lab @kcrow11.bsky.social
June 11, 2025 at 6:10 PM
POV: you venture over to the #celegans side of the lab @kcrow11.bsky.social
This and yap
April 8, 2025 at 10:07 PM
This and yap
This week, I was invited as the Alumni speaker for the Stupka Undergraduate Research Symposium in BBMB at Iowa State University. Sharing my research with my alma mater was a true honor, a highlight of graduate school, and definitely a full circle moment. I am so lucky!
April 6, 2025 at 10:26 PM
This week, I was invited as the Alumni speaker for the Stupka Undergraduate Research Symposium in BBMB at Iowa State University. Sharing my research with my alma mater was a true honor, a highlight of graduate school, and definitely a full circle moment. I am so lucky!
I needed my column to continue washing while I was in lab meeting so I grabbed one of those pesky slow columns et voilà! She’s an innovator today 🤭
March 21, 2025 at 7:51 PM
I needed my column to continue washing while I was in lab meeting so I grabbed one of those pesky slow columns et voilà! She’s an innovator today 🤭
Celebrating #internationalwomensday and #womenshistorymonth with this inspiring little read. Bookmarking it with the leather tab made by one of my favorite women, my mom.
March 9, 2025 at 3:51 AM
Celebrating #internationalwomensday and #womenshistorymonth with this inspiring little read. Bookmarking it with the leather tab made by one of my favorite women, my mom.
Post #bps2025 checklist:
laundry ✅
purify proteins ✅
tell literally everyone how inspired & motivated u are since coming back from LA … ✅
@kcrow11.bsky.social
laundry ✅
purify proteins ✅
tell literally everyone how inspired & motivated u are since coming back from LA … ✅
@kcrow11.bsky.social
February 26, 2025 at 12:26 AM
Post #bps2025 checklist:
laundry ✅
purify proteins ✅
tell literally everyone how inspired & motivated u are since coming back from LA … ✅
@kcrow11.bsky.social
laundry ✅
purify proteins ✅
tell literally everyone how inspired & motivated u are since coming back from LA … ✅
@kcrow11.bsky.social
Reposted by Jacqueline Ehrlich
Had such an amazing time at my first BPS conference! Looking forward to BPS 2026 already!
#bps2025
@jacquelineehrlich.bsky.social @saketbagde.bsky.social @biophysicalsoc.bsky.social
#bps2025
@jacquelineehrlich.bsky.social @saketbagde.bsky.social @biophysicalsoc.bsky.social
February 20, 2025 at 12:37 AM
Had such an amazing time at my first BPS conference! Looking forward to BPS 2026 already!
#bps2025
@jacquelineehrlich.bsky.social @saketbagde.bsky.social @biophysicalsoc.bsky.social
#bps2025
@jacquelineehrlich.bsky.social @saketbagde.bsky.social @biophysicalsoc.bsky.social
Multitaskin’ this morning
January 21, 2025 at 4:31 PM
Multitaskin’ this morning
Joining the @bsky.app party just in time to share my 1st cryo-EM structures from our latest Panx1 story in @pnas.org! I’m so grateful for Cornell’s cryo-EM community (esp @fromme-lab.bsky.social @cryomariena.bsky.social @10feng.bsky.social) in helping us establish cryoEM in our lab the last 5 years!
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
January 3, 2025 at 2:23 AM
Joining the @bsky.app party just in time to share my 1st cryo-EM structures from our latest Panx1 story in @pnas.org! I’m so grateful for Cornell’s cryo-EM community (esp @fromme-lab.bsky.social @cryomariena.bsky.social @10feng.bsky.social) in helping us establish cryoEM in our lab the last 5 years!