j-openy.bsky.social
@j-openy.bsky.social
Reposted by j-openy.bsky.social
New PhD opportunity in the 't Hart group! We are looking for a candidate interested in using a chemical biology approach to study mRNA degradation. The project will focus on AI-generated peptide inhibitors to study mRNA deadenylation.
stellen.uni-muenster.de/jobposting/7...
stellen.uni-muenster.de/jobposting/7...
Doctoral Research Associate (Wissenschaftliche*r Mitarbeiter*in,salary level E 13 TV-L)
stellen.uni-muenster.de
October 20, 2025 at 9:33 AM
New PhD opportunity in the 't Hart group! We are looking for a candidate interested in using a chemical biology approach to study mRNA degradation. The project will focus on AI-generated peptide inhibitors to study mRNA deadenylation.
stellen.uni-muenster.de/jobposting/7...
stellen.uni-muenster.de/jobposting/7...
Reposted by j-openy.bsky.social
I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.
September 5, 2025 at 5:41 AM
I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.
Reposted by j-openy.bsky.social
My first post here on Bluesky! Highlighting our preprint looking at how backbone modifications influence cyclic peptide cell uptake. Turns out it is a balancing act between uptake and biological activity. Great work by first author Joseph Openy and of course all others!
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Single atom substitutions in backbone aromatic groups alter membrane permeability and biological activity of cyclic peptides
Cyclic peptides hold significant potential as disruptors of challenging targets such as protein-protein interactions, but their poor membrane permeability often limits their use for intracellular targ...
chemrxiv.org
January 27, 2025 at 10:29 AM
My first post here on Bluesky! Highlighting our preprint looking at how backbone modifications influence cyclic peptide cell uptake. Turns out it is a balancing act between uptake and biological activity. Great work by first author Joseph Openy and of course all others!
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...