Excited to share our study on #neutrophils in brain cancers – now online in #Cell!
 
Neutrophils migrate to the #brain #TME in large no's & adopt multifaceted tumor-promoting roles 🧵⬇️
 
🙏 to all in our super team 🧪⚕️, led by Roeltje Maas 🙌
 
Image: @joanagcc.bsky.social
 
www.cell.com/cell/fulltex...

🧪🧪 The Immunological Proteome Resource is now on Bluesky as well.

ImmPRes is an open access resource created to provide an in-depth, high quality, quantitative map of the immuno proteome. It integrates immune cell proteomic data generated by quantitative mass-spectrometry.

#immunology #proteomics

Thrilled to announce a new preprint developing a new grammar in @PhysiCell to bridge biological, clinical, and systems biology researchers for mathematical modeling of biological systems at scale including integration of single-cell multi-omics data. 1/19 www.biorxiv.org/content/10.1...

Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity
www.nature.com/articles/s41...

Cool paper, thanks @timtriche.bsky.social

🧬🖥️⚕️🔬🧫💊 #immunosky

Our lab’s review on antibody drug conjugates just came out in JCI! We discuss some of their immune stimulatory properties and also how they can help create drugs of the future. Check it out here if you’re curious! www.jci.org/articles/vie... 🧪

🧪 A gene variant found in 20-30% of individuals seems to lessen the risk of Alzheimer's and Parkinson's. Analysis involved data from 176k patients, nearly 2 million controls, and 7k autopsied brains, pinpointing lower risks & reduced abnormal brain proteins.

Welcome @hoadley.bsky.social!

We should get all of UNC's Computational Medicine program on here.

🧪🧬🖥️⚕️🔬🧫💊

Are you an R user who is interested in learning Python?

This blog from Rebecca Barter introduces Python from an R user's perspective 🧪

www.rebeccabarter.com/blog/2023-09...

Tumors can have diverse mitochondrial charge levels, respiration, and shapes. More cool evidence that we can measure this in vivo in mammals and that it's relevant for health: 🧪

idp.nature.com/authorize?re...

Excited to have this Opinion out! We propose that the diverse functions of Treg cells in health and disease may be interpreted in terms of different dynamical regimes of an immune cell circuit, which provides a powerful framework for analyzing experimental data.
www.sciencedirect.com/science/arti...

Complexity of the wireless connectome in C. elegans. Important work setting the stage look at biological roles of this signaling in vivo 👏
🧪 #neuroscience
www.cell.com/cell-reports...

Interesting review, does model complexity ⬆️ understanding?

“If classical algorithms are divided from human understanding, they are also divided from data…Machine learning changes this. The “algorithms” are no longer designed by engineers but instead tuned by machines based on large amounts of data”

@danirabaiotti.bsky.social could I be added to the science 🧪 feed? I’m interested in designing new immunotherapies to treat metastatic cancer using natural killer cells!

I hope with all the twitter changes occurring, bluesky can become a source where we can discover new exciting papers.

Also hello bluesky, first post etc. I’m into making new cancer immunotherapies and natural killer cells 🧪