@ish1789.bsky.social
Reposted
Our latest preprint. More evidence that diabetic neuropathy is a neuro degenerative disease. Very proud of @ish1789.bsky.social and our whole PRECISION group who made this work possible. #HEALinitiative funded
Progressive neurodegeneration in human dorsal root ganglion from diabetes to painful neuropathy https://www.biorxiv.org/content/10.64898/2026.01.16.700028v1
January 21, 2026 at 2:34 AM
Our latest preprint. More evidence that diabetic neuropathy is a neuro degenerative disease. Very proud of @ish1789.bsky.social and our whole PRECISION group who made this work possible. #HEALinitiative funded
Reposted
Also happy to see that our rat DRG dataset is now online at Journal of Pain. www.jpain.org/article/S152... Big thanks to Sydney Caparaso and Becky Wachs for leading this effort along with @ish1789.bsky.social and I. Rats and mice and humans are not the same, oh my!
Single-nuclei RNA Sequencing Reveals Distinct Transcriptomic Signatures of Rat Dorsal Root Ganglia in a Chronic Discogenic Low Back Pain Model
Chronic low back pain (LBP), often correlated with intervertebral disc degeneration,
is a leading source of disability worldwide, yet remains poorly understood. Current
treatments often fail to provid...
www.jpain.org
November 7, 2025 at 5:51 PM
Also happy to see that our rat DRG dataset is now online at Journal of Pain. www.jpain.org/article/S152... Big thanks to Sydney Caparaso and Becky Wachs for leading this effort along with @ish1789.bsky.social and I. Rats and mice and humans are not the same, oh my!
Reposted
The BIG DRG paper is now up on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1... so many people worked so hard to make this happen. Props to the whole PRECISION Human Pain Network.
A Reference Atlas of the Human Dorsal Root Ganglion
Somatosensory perception largely emerges from diverse peripheral sensory neurons whose cell bodies reside in dorsal root ganglia (DRG). Damage or dysfunction of DRG neurons is a major cause of chronic...
www.biorxiv.org
November 7, 2025 at 11:16 AM
The BIG DRG paper is now up on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1... so many people worked so hard to make this happen. Props to the whole PRECISION Human Pain Network.