@irobcross.bsky.social
In BIORXIV/2025/651652, we use ATPγS to reveal a previously-occult kinesin state. In the Await-Isomerisation (AI) state, ATP is bound but NL docking and hydrolysis are inhibited. ATPγS overstabilises the AI state, producing a characteristic signature of load-independent 8 nm tethered backslips:
May 2, 2025 at 10:10 AM
In BIORXIV/2025/651652, we use ATPγS to reveal a previously-occult kinesin state. In the Await-Isomerisation (AI) state, ATP is bound but NL docking and hydrolysis are inhibited. ATPγS overstabilises the AI state, producing a characteristic signature of load-independent 8 nm tethered backslips: