IorioLab
@ioriolab.bsky.social
we mix informatics/biology/functional-genomics to identify new therapeutic targets/markers, for cancer and other human diseases. we ❤️ CRISPR, statistics and ML
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
October 29, 2025 at 1:38 PM
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
October 29, 2025 at 1:37 PM
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
October 29, 2025 at 1:34 PM
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
October 29, 2025 at 1:33 PM
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
The Iorio Lab is at the 37th AICC International Meeting in Florence this week. With our Francesco Iorio presenting as an invited speaker, Nevenka Radic with a flash talk and Vanessa Spagnolo with a poster. Excited to share our latest results and connect with colleagues in the field.
October 29, 2025 at 1:30 PM
The Iorio Lab is at the 37th AICC International Meeting in Florence this week. With our Francesco Iorio presenting as an invited speaker, Nevenka Radic with a flash talk and Vanessa Spagnolo with a poster. Excited to share our latest results and connect with colleagues in the field.
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
October 29, 2025 at 1:19 PM
Kudos to Nevenka Radic for winning the best poster award! Very well deserved 🎉
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
October 29, 2025 at 1:15 PM
Francesco Iorio’s invited talk highlights how we integrate clinically relevant mutational profiles with CRISPR functional genomics data to uncover vulnerabilities associated with mutations currently considered non-actionable, expanding potential therapeutic opportunities.
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
October 29, 2025 at 1:11 PM
Vanessa Spagnolo presents how we dissect cancer dependencies using CRISPR functional genomics, and how we are applying these approaches across multiple projects in our lab to identify new therapeutic vulnerabilities.
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
October 29, 2025 at 1:10 PM
Nevenka Radic is showcasing our work charting the genetic dependencies of drug-resistant cancer cells. By identifying context-specific vulnerabilities, we aim to inform the rational design of combinatorial treatments to advancing precision oncology.
Kudos to our Flavio Passante for winning with his team the REMEDi4ALL Hackathon in Barcellona! Researchers from 10 countries tackled real-world challenges in drug repurposing for rare neurodevelopmental disorders, spanning the whole pipeline from early target discovery to market access.
October 23, 2025 at 11:48 AM
Kudos to our Flavio Passante for winning with his team the REMEDi4ALL Hackathon in Barcellona! Researchers from 10 countries tackled real-world challenges in drug repurposing for rare neurodevelopmental disorders, spanning the whole pipeline from early target discovery to market access.
Our very own Raffaele Iannuzzi successfully defended his PhD Thesis last week. Raf has worked on benchmarking CRISPRdata analytical tool and predictive models leveraging bulk & single cell RNA-seq data. We will definitely miss him. We wish him all the best as new adventures await! Congrats Raf! 🎉
October 22, 2025 at 7:23 AM
Our very own Raffaele Iannuzzi successfully defended his PhD Thesis last week. Raf has worked on benchmarking CRISPRdata analytical tool and predictive models leveraging bulk & single cell RNA-seq data. We will definitely miss him. We wish him all the best as new adventures await! Congrats Raf! 🎉
!!! Less than 2 weeks left to register !!! Join us in Milan for the 2nd European Cancer Dependency Map Symposium, taking place on 20 November 2025 at Human Technopole
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
October 21, 2025 at 10:08 AM
!!! Less than 2 weeks left to register !!! Join us in Milan for the 2nd European Cancer Dependency Map Symposium, taking place on 20 November 2025 at Human Technopole
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Cancer functional genomics; CRISPR-based screening;
AIdriven targetDiscovery and drug development
humantechnopole.it/en/trainings...
Last week we had the pleasure of hosting @maxbillmann.bsky.social at @humantechnopole.bsky.social for an inspiring seminar on genetic interaction maps an networks. Fantastic to learn how CRISPR screens and integrative analyses can illuminate the logic of genetic dependencies. A big thank you Max 👏
October 21, 2025 at 8:57 AM
Last week we had the pleasure of hosting @maxbillmann.bsky.social at @humantechnopole.bsky.social for an inspiring seminar on genetic interaction maps an networks. Fantastic to learn how CRISPR screens and integrative analyses can illuminate the logic of genetic dependencies. A big thank you Max 👏
Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
September 11, 2025 at 12:33 PM
Today we bid farewell to our postDoc @aurorasavino.bsky.social, who is moving to an independent position at the University of Torino. Her talent dedication and collaborative spirit have left a lasting mark on our team and projects🎉
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
Wishing you all the best for this exciting next chapter, Aurora!
🥳🍾
we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social
@humantechnopole.bsky.social
June 18, 2025 at 11:57 AM
we are at #EACR2025 with two posters - the second one is presented by Ludovica Proietti and Gianluca vozza and focuses on our ERC funded DEPshock project
@humantechnopole.bsky.social
@humantechnopole.bsky.social
we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social
June 18, 2025 at 7:32 AM
we are at #EACR2025 with two posters, one presented by our Ottavio Croci on our collaborative work around a CRISPR based prioritisation of lncRNA vulnerabilities in multiple myeloma @humantechnopole.bsky.social
Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates
June 12, 2025 at 7:38 PM
Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates
🎄🎁 Secret Santa at IorioLab! 🎁🎄
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
December 12, 2024 at 8:23 PM
🎄🎁 Secret Santa at IorioLab! 🎁🎄
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
Today, we swapped gifts, laughs, and maybe a few too many inside jokes during our Secret Santa exchange. From creative surprises to hilariously overwrapped packages, everyone brought the holiday cheer 👍 merry Xmas
Amazing Bavarian-style @humantechnopole.bsky.social CompBiol Centre Xmas Dinner w @bioimagecomputing.com @sottoriva.bsky.social and other labs 🍺🎄👍💻🧬
December 10, 2024 at 6:44 PM
Amazing Bavarian-style @humantechnopole.bsky.social CompBiol Centre Xmas Dinner w @bioimagecomputing.com @sottoriva.bsky.social and other labs 🍺🎄👍💻🧬
🎓 Huge congratulations to Irene FernandezRebollo
and @alessandrodigilio.bsky.social on graduating and successfully defending their master theses on cancer-specific epigenetic clocks! 🧬🕒 Wishing you both great success in your next adventures @manelesteller.bsky.social @humantechnopole.bsky.social
and @alessandrodigilio.bsky.social on graduating and successfully defending their master theses on cancer-specific epigenetic clocks! 🧬🕒 Wishing you both great success in your next adventures @manelesteller.bsky.social @humantechnopole.bsky.social
November 28, 2024 at 9:44 PM
🎓 Huge congratulations to Irene FernandezRebollo
and @alessandrodigilio.bsky.social on graduating and successfully defending their master theses on cancer-specific epigenetic clocks! 🧬🕒 Wishing you both great success in your next adventures @manelesteller.bsky.social @humantechnopole.bsky.social
and @alessandrodigilio.bsky.social on graduating and successfully defending their master theses on cancer-specific epigenetic clocks! 🧬🕒 Wishing you both great success in your next adventures @manelesteller.bsky.social @humantechnopole.bsky.social
Kudos to our Flavio Passante for presenting his work on new computational approaches for #drug_repurposing within the NEUROCOV-eu consortium @humantechnopole.bsky.social at the SEMM PhD-student Retreat 2024 and for winning the best poster prize award 🥳🥳
November 22, 2024 at 11:18 AM
Kudos to our Flavio Passante for presenting his work on new computational approaches for #drug_repurposing within the NEUROCOV-eu consortium @humantechnopole.bsky.social at the SEMM PhD-student Retreat 2024 and for winning the best poster prize award 🥳🥳