IOB - Institute of Molecular and Clinical Ophthalmology Basel
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IOB - Institute of Molecular and Clinical Ophthalmology Basel
@iobswiss.bsky.social
Where Science Meets Vision

At the Institute of Molecular and Clinical Ophthalmology Basel (IOB), our mission is to advance the understanding of vision and its diseases, and to develop new therapies for vision loss.
Can a blind retina be made sensitive to infrared light? Our team shows that an engineered human TRPV1 channel, delivered by AAV, elicits robust responses without foreign proteins or nanoparticles.
🔗 bit.ly/4gt0LO5
#AcademicBlueSky #ProteinEngineering #TRPChannels #SyntheticBiology #Vision #Retina
September 18, 2025 at 1:00 PM
🧬 How can we navigate the genetic complexity of inherited retinal diseases?
Our new paper in @ajhgnews.bsky.social presents RetiGene, a curated atlas of IRD genes, built with @erdc-team.bsky.social, to support diagnosis, research and therapy.
👉 bit.ly/467U1S9
#AcademicBlueSky #IRDs #VisionResearch
September 16, 2025 at 11:04 PM
🔬👁️ Organoids in the spotlight!
Magdalena Renner, leading IOB’s organoid platform, shares how high-throughput organoid systems are transforming research and speeding up the path to therapies for eye diseases. Read more: bit.ly/4mquwjP
#VisionResearch #HistoBrick #Blindness #Retina #AcademicBlueSky
September 16, 2025 at 10:30 PM
👏Warm congratulations to our former IOB postdoctoral fellow @fionamuellner.bsky.social on her new role as Group Leader at @dandrite.bsky.social & Associate Professor at Aarhus University — and on receiving a prestigious ERC Starting Grant!
@erc.europa.eu
September 9, 2025 at 3:38 PM
This changes how we think about vision: timing coordination starts in the eye - not the brain! Check out @anbucci.bsky.social & @ffranke.bsky.social's discovery: nature.com/articles/s41...
#Neuroscience #Vision #RGCs #RetinalResearch #AcademicBlueSky #EyeResearch #ScientificDiscovery
August 14, 2025 at 12:06 PM
🧠👁️ How does your eye prevent seeing a scrambled world? @anbucci.bsky.social and @ffranke.bsky.social reveal the eye's secret "clockwork": bigger axons = faster signals = perfect visual timing!
📖 Full paper nature.com/articles/s41593-025-02011-3
#Vision #AcademicSky #Neuroscience #Retina
Image ©IOB
August 13, 2025 at 10:53 AM
🧬👁️Discover how research and patient care come together in the latest Novartis Live magazine — with stories from the labs and clinics shaping the future of vision.

🔗 bit.ly/4km6XZ0

#IOB #VisionScience #TranslationalResearch #Basel #Ophthalmology #AcademicSky #Novartis
May 13, 2025 at 3:56 PM
What controls eye growth?
10 key insights from decades of myopia research - from retinal feedback to red light therapy, here is what we know:
🔗 onlinelibrary.wiley.com/doi/10.1111/...

#Myopia #VisionResearch #Ophthalmology #GlobalHealth #AcademicBlueSky

Image © IOB, generated with Google AI, 2025
April 16, 2025 at 1:18 PM
🧬IOB researchers (@Mukhtarullah.bsky.social
@karkam.bsky.social @carlorivolta.bsky.social
@mquinodoz.bsky.social) and international team uncover genetic signatures of eye diseases in Pakistan
📖 doi.org/10.1038/s415...
#Genetics #Vision #AcademicSky

Image © IOB, generated with Google AI, Gemini
April 15, 2025 at 4:51 PM
🧠 Brain efficiency doesn't need perfect organization

Random neural responses can lead to better information processing than precisely tuned ones.

www.sciencedirect.com/science/arti...

@ravadasilveira.bsky.social | image © IOB, 2025
#AcademicSky #Neuroscience #ScienceNews
March 21, 2025 at 6:46 AM
🧠 How does your brain create mental maps?

New research reveals a surprisingly simple mathematical principle behind complex spatial representations! From rodents to bats, same rules apply 🐁🦇

#Neuroscience #BrainScience #ScienceNews #AcademicBluesky

Read more here: www.cell.com/neuron/fullt...
February 24, 2025 at 4:52 PM
🔍 Did you ever wonder why your eyes make tiny movements even when trying to hold still?

Those movements are not a bug, they are an essential feature for sharp vision!

Here is why: www.pnas.org/doi/epub/10....

#AcademicSky #Neuroscience #Ophthalmology

Illustration ©IOB, 2025
February 11, 2025 at 7:57 AM
👁️ Advancing Vision Research 👁️
Our latest study with collaborators from CSEM introduces a HistoBrick array made from a novel material mix, optimizing cryosectioning and immunohistochemistry for retinal organoids and small tissues.

📖 Learn more: rdcu.be/d5o8Z
#Organoids #AcademicSky
Picture © IOB
January 21, 2025 at 5:32 PM
We are pleased to share that RhyGaze, IOB's first spin-off, has secured Series A funding with an USD 86 million investment to advance vision restoration therapy.

Read more: iob.ch/news-view-al...

#Biotech #Basel #Innovation #LifeSciences #GeneTherapy #Ophthalmology #RhyGaze #BioTechHub
January 10, 2025 at 2:26 PM
✨Thrilled about our new publication in Nature Medicine! We are excited to offer a potential new avenue for treating Stargardt disease!
Read the paper here: nature.com/articles/s41...
Watch the video: iob.ch/fileadmin/ge...
Press release here: iob.ch/news-view-al...

© 2025 IOB
January 8, 2025 at 7:40 PM
✨Scientific breakthrough: IOB researchers have achieved a significant advance in developing a new treatment for Stargardt disease, the most common form of inherited macular degeneration.
Read more: www.nature.com/articles/s41...
Watch full movie: iob.ch/news-view-al...
#AcademicSky #neuroscience
January 8, 2025 at 1:58 PM