🌍 World AMR Awareness Week 2025 | Preventing antimicrobial resistance together

Antimicrobial resistance (AMR) remains one of the biggest threats to global health - demanding innovation, collaboration, & better understanding of how we use antibiotics in clinical care.

Read more tinyurl.com/yw792han

INHALE WP3 RCT health economic analysis now published in Critical Care.
The Pneumonia Panel PCR had lower average ICU costs and was cost effective for antimicrobial stewardship, but not clinical cure.

Read in full at: rdcu.be/eAmSD

‘INHALE Poem II – A slight diversion’ shares the journey of the INHALE study, describing its hopes, challenges and the implications of the research.
This poem was written and performed by Amander Wellings, of the INHALE Patient, Carer and Public Involvement (PPI) group.

youtu.be/-UUBzbSmEo0?...

What is the impact of seeking pathogens by rapid molecular diagnostic methods on antibiotic stewardship and the clinical outcomes in hospital-acquired and ventilator-associated pneumonia (HAP and VAP)?

Visual abstract below and full paper available online at rdcu.be/ehlAu

Our call to to resistance, led by @angelahuttner.bsky.social and first published in @cmicomms.bsky.social, now published in @cmijournal.bsky.social too

www.clinicalmicrobiologyandinfection.com/article/S119...

INHALE compared rapid testing with standard care used to diagnose pneumonia in intensive care. Rapid testing gave faster results than standard care and improvements in antibiotic use. But, the machine did not improve cure of pneumonia, so more research is needed to understand why.

1/4 Rapid molecular diagnostic tests for pathogens and resistance genes may improve antibiotic prescribing decisions and stewardship. However, clinicians’ desire to protect their patient with an antibiotic often overrides more distal concerns about possible resistance selection,

🚨 New Paper from Dr SJ Stewart and the INHALE team @inhale-trial.bsky.social

“Guidelines vs Mindlines” published in Antimicrobial Agents and Chemotherapy

journals.asm.org/doi/10.1128/...

1/2 The INHALE WP3 randomised trial provides multi-centre evidence that rapid syndromic PCR, delivered at the point-of care in the ICU improved antibiotic stewardship by 21% in absolute terms. Equivalence of clinical cure was not demonstrated link.springer.com/article/10.1...