Michał Jastrzębski
@inc0.bsky.social
Putting proteins on kubernetes. Chanter of genomic canticles. Breeding dragons at Ginkgo. Curiosity drives the cat.
Hello bio friends, I need help. I'm looking for dataset to evaluate my codon optimization tool for weird organisms. I'm looking for any data that shows multiple codings of the same protein expressed in any organism and measured the expression. Like codings of gfp in ecoli
November 18, 2025 at 10:22 PM
Hello bio friends, I need help. I'm looking for dataset to evaluate my codon optimization tool for weird organisms. I'm looking for any data that shows multiple codings of the same protein expressed in any organism and measured the expression. Like codings of gfp in ecoli
Hey fellow bio kids! Does anyone know cheap, diy and scrappy cell lysis buffer? Something that'll melt yeast and other common bugs. Trying to get into metagenomics
February 12, 2025 at 8:00 PM
Hey fellow bio kids! Does anyone know cheap, diy and scrappy cell lysis buffer? Something that'll melt yeast and other common bugs. Trying to get into metagenomics
Reposted by Michał Jastrzębski
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:21 PM
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
Reposted by Michał Jastrzębski
Super excited to announce our latest flagship model Borzoi: major props to Johannes & David Kelley et al for advancing it. It's been a long journey from our prior Enformer model into this one. A few innovations: i) longer DNA context, ii) adaptation to predict RNA-seq abundance and splice isoforms,
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation - Nature Genetics
Borzoi adapts the Enformer sequence-to-expression model to directly predict RNA-seq coverage, enabling the in-silico analysis of variant effects across multiple layers of gene regulation.
www.nature.com
January 9, 2025 at 3:08 AM
Super excited to announce our latest flagship model Borzoi: major props to Johannes & David Kelley et al for advancing it. It's been a long journey from our prior Enformer model into this one. A few innovations: i) longer DNA context, ii) adaptation to predict RNA-seq abundance and splice isoforms,
Hey! I wrote a thing! github.com/ginkgobiowor... This is a tutorial on how to use deep learning to solve scientific problems without being an ML scientist. Use the Ginkgo API to predict all sorts of things. Lmk what you think
GitHub - ginkgobioworks/ginkgoai-protein-embedding-tutorial: Tutorial on how to use Ginkgo AI embedding APIs for scientific problems
Tutorial on how to use Ginkgo AI embedding APIs for scientific problems - ginkgobioworks/ginkgoai-protein-embedding-tutorial
github.com
November 22, 2024 at 5:54 PM
Hey! I wrote a thing! github.com/ginkgobiowor... This is a tutorial on how to use deep learning to solve scientific problems without being an ML scientist. Use the Ginkgo API to predict all sorts of things. Lmk what you think
RIP Netflix servers
November 16, 2024 at 5:01 AM
RIP Netflix servers
Reposted by Michał Jastrzębski
This is 100% true. I’ve been seeing this for a while. Knowing how things work deeply is a super power, and one you can use to create better products.
In the age of AI, short form video and hot takes, the competitive advantage of the future is the ability to go deep, read the docs, build something new, learn hard things that take time.
November 15, 2024 at 3:26 PM
This is 100% true. I’ve been seeing this for a while. Knowing how things work deeply is a super power, and one you can use to create better products.
If this holds up, then we're so back www.biorxiv.org/content/10.1...
Revolutionizing large-scale DNA synthesis with microchip-based massive in parallel synthesis system
DNA synthesis serves as the fundamental enabling technology of engineering biology, aiming to provide DNA molecules of designed composition, length, and complexity at scale and low cost. Current high-...
www.biorxiv.org
November 1, 2024 at 7:20 PM
If this holds up, then we're so back www.biorxiv.org/content/10.1...
Reposted by Michał Jastrzębski
For #microbiology #phage folks of bsky - can I get some recommendations for review/landmark papers on Siphoviridae tail genomics/morphology/phylogenetics? I'm running into walls on how to interpret some recent observations & thinking maybe reviews will turn up something 🧪
September 9, 2023 at 11:02 PM
For #microbiology #phage folks of bsky - can I get some recommendations for review/landmark papers on Siphoviridae tail genomics/morphology/phylogenetics? I'm running into walls on how to interpret some recent observations & thinking maybe reviews will turn up something 🧪
Reposted by Michał Jastrzębski
September 5, 2023 at 12:59 AM
This winter was long and rainy in PNW. There are some perks to this weather tho.
May 24, 2023 at 4:56 AM
This winter was long and rainy in PNW. There are some perks to this weather tho.
Hey everyone! I see a lot of ML and cloud friends here! Any biology and bioinformatics folk around?
April 23, 2023 at 11:46 PM
Hey everyone! I see a lot of ML and cloud friends here! Any biology and bioinformatics folk around?